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Expectations and Experiences of Participating in a Supervised and Home-Based Physical Exercise Intervention in Patients with Head and Neck Cancer during Chemoradiotherapy

Kok, Annemieke; Passchier, Ellen; May, Anne M; Jager-Wittenaar, Harriët (Healthy Ageing, Allied Health Care And Nursing); Veenhof, Cindy; de Bree, Remco; Stuiver, Martijn M; Speksnijder, Caroline M

(1) Background: Chemoradiotherapy (CRT) for head and neck cancer (HNC) is associated with severe toxicity resulting in fatigue and weight loss, including loss of skeletal muscle mass. Exercise interventions might positively affect physical fitness and quality of life. Sufficient adherence and compliance …

2024-02-04AlgemeenArtikel

Feasibility of a supervised and home-based tailored exercise intervention in head and neck cancer patients during chemoradiotherapy

Kok, Annemieke; Passchier, Ellen; May, Anne M.; van den Brekel, Michiel W. M.; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Veenhof, Cindy; de Bree, Remco; Stuiver, Martijn M; Speksnijder, Caroline M.

Objective: Chemoradiotherapy (CRT) for head and neck cancer (HNC) is associated with high toxicity that adversely affects physical functioning, body composition, fatigue, quality of life and treatment outcomes. Exercise interventions during treatment might counteract these negative effects. We therefore …

2022-08-11AlgemeenArtikel

Immune monitoring of T cell and NK cell subsets of non-small cell lung cancer patients receiving neoadjuvant treatment with Chemoradiotherapy, Nivolumab, and Ipilimumab

HL Prijs 2022

Non-small cell lung cancer (NSCLC) occurs in approximately 80-85% of all lung cancer patients and has a 5-year overall survival (OS) of only 15-20%. In this study, 29 NSCLC patients received neoadjuvant treatment with Chemoradiotherapy, Nivolumab, and Ipilimumab. This study aimed to investigate the effects …

2022-06-14GezondheidBachelor

Decrease of physical fitness during neoadjuvant chemoradiotherapy predicts the risk of pneumonia after esophagectomy

Petra Bor; Feike Kingma; Ad Kerst; Elles Steenhagen; Jelle Ruurda; Richard van Hillegersberg; Karin Valkenet (Lid Lectoraat); Cindy Veenhof (Lector)

Although neoadjuvant chemoradiotherapy (nCRT) is frequently used in esophageal cancer patients undergoing treatment with curative intent, it can negatively impact patients’ physical fitness. A decline in physical fitness during chemoradiotherapy may be an indication of vulnerability. The aim of this …

2021GezondheidArtikel

Ondervoeding bij NSCLC-stadium III

Amarins Koster (Student); Tessa Sluiter (Student); Wouter Schaake (Begeleider); Esther Gerbers-van den Heuvel (Begeleider)

Het doel van dit onderzoek is om te identificeren welke factoren invloed hebben op het gewichtsverlies tijdens de chemoradiatie van patiënten met NSCLC-stadium III. Door deze factoren te bepalen, kan hier mogelijk preventief op worden ingespeeld tijdens het behandelproces. Van de NSCLC-stadium III patiënten …

2020-06-08GezondheidBachelor

Nutrition status and health-related quality of life among outpatients with advanced head and neck cancer

Mulasi, Urvashi; Vock, D.M.; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Teigen, L.; Kuchnia, A.J.; Jha, G.; Fujioka, N.; Rudrapatna, V.; Patel, M.R.; Earthman, Carrie

This pilot study evaluated nutrition status and health-related quality of life (HRQOL) outcomes among outpatients with head and neck cancer (HNC). Data were collected from 19 patients (18 males, 1 female) during 3 time points: once before chemoradiotherapy (CRT) initiation and 1 and 3 months after CRT. …

2020-03AlgemeenArtikel

Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update

Karsten, Rebecca T.; van der Molen, Lisette; Hamming-Vrieze, Olga; van Son, RobJ. J. J. H.; Hilgers, Frans J. M.; van den Brekel, Michiel W. M.; Stuiver, Martijn M (Centre Of Expertise Urban Vitality); Smeele, Ludi E.

BACKGROUND: The objective of this study was to explore the 10-year plus outcomes of Intensity Modulated Radiotherapy with concomitant chemotherapy (CRT) combined with preventive swallowing rehabilitation (CRT+) for head and neck cancer (HNC). METHODS: Subjective and objective swallowing, trismus, and …

2020AlgemeenArtikel

Improving Decision Making in Larynx Cancer by Developing a Decision Aid: A Mixed Methods Approach

Petersen, Japke F.; Berlanga, Adriana; Stuiver, Martijn M. (Faculteit Gezondheid); Hamming-Vrieze, Olga; Hoebers, Frank; Lambin, Philippe; van den Brekel, Michiel W.M.

OBJECTIVE: Patients diagnosed with advanced larynx cancer face a decisional process in which they can choose between radiotherapy, chemoradiotherapy, or a total laryngectomy with adjuvant radiotherapy. Clinicians do not always agree on the best clinical treatment, making the decisional process for patients …

2019-12AlgemeenArtikel

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy

Beck, Ann-Jean C C; Passchier, Ellen; Retèl, Valesca P; Stuiver, Martijn M (Centre Of Expertise Urban Vitality); van der Molen, Lisette; Klop, Willem M C; Navran, Arash; van Harten, Wim H; van den Brekel, Michiel W M

BACKGROUND: Since 2011, a tailored, interdisciplinary head and neck rehabilitation (IHNR) program, covered by the basic healthcare insurance, is offered to advanced head and neck cancer (HNC) patients in the Netherlands Cancer Institute (NKI). This program is developed to preserve or restore patients' …

2019-07-03AlgemeenArtikel

Radiation dose to the masseter and medial pterygoid muscle in relation to trismus after chemoradiotherapy for advanced head and neck cancer

Sophie A. Kraaijenga; Olga Hamming-Vrieze; Sonja Verheijen; Emmy Lamers (Lid Lectoraat); Lisette van der Molen; Frans J. Hilgers; Michiel W. van den Brekel; Wilma D. Heemsbergen

Abstract Background: We studied the relationship between trismus (maximum interincisor opening [MIO] ≤35 mm) and the dose to the ipsilateral masseter muscle (iMM) and ipsilateral medial pterygoid muscle (iMPM). Methods: Pretreatment and post-treatment measurement of MIO at 13 weeks revealed 17% of …

2019GezondheidArtikel

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