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Airway Mucus in Invasively Ventilated Critically Ill Patients

Stilma, Willemke (Faculteit Gezondheid); Lilien, Thijs A; Bos, Lieuwe DJ; Saatpoor, Aryen; Elsayed, Omar; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Bem, Reinout A; Linssen, Rosalie SN

Patients who are critically ill and receiving invasivemechanical ventilation are at increased risk for accumula-tion of secretions in the lower airways. Such accumula-tion of airway mucus can induce atelectasis and contributeto ventilator-associated pneumonia. Preventive airwaycare interventions, including …

2023-09-01AlgemeenArtikel

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

A closed-loop ventilation mode that targets the lowest work and force of breathing reduces the transpulmonary driving pressure in patients with moderate-to-severe ARDS

Buiteman-Kruizinga, Laura A.; van Meenen, David M. P.; Bos, Lieuwe D. J.; van der Heiden, Pim L. J.; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

Introduction The driving pressure (ΔP) has an independent association with outcome in patients with acute respiratory distress syndrome (ARDS). INTELLiVENT-Adaptive Support Ventilation (ASV) is a closed-loop mode of ventilation that targets the lowest work and force of breathing. Aim To compare transpulmonary …

2023AlgemeenArtikel

Association between characteristics of nursing teams and patients' aggressive behavior in closed psychiatric wards

Doedens, Paul (Centre Of Expertise Urban Vitality); Vermeulen, Jentien; ter Riet, Gerben (Lectoraat Voeding En Beweging); Boyette, Lindy Lou; Latour, Corine (Lectoraat Geïntegreerde Complexe Zorg); de Haan, Lieuwe

Purpose: Estimate the effect of nursing, shift, and patient characteristics on patients' aggression. Design and Methods: Follow-up study on a closed psychiatric ward was performed to estimate the effect of nursing team characteristics and patient characteristics on the incidence of aggression. Findings: …

2022-10AlgemeenArtikel

Cross-classified multilevel models improved standard error estimates of covariates in clinical outcomes – a simulation study

Doedens, Paul (Centre Of Expertise Urban Vitality); ter Riet, Gerben (Faculteit Gezondheid); Boyette, Lindy-Lou; Latour, Corine (Lectoraat Geïntegreerde Complexe Zorg); de Haan, Lieuwe; Twisk, Jos

Objective To compare estimates of effect and variability resulting from standard linear regression analysis and hierarchical multilevel analysis with cross-classified multilevel analysis under various scenarios. Study design and setting We performed a simulation study based on a data structure from an …

2022-05AlgemeenArtikel

Unlock the doors

Doedens, Paul (Lectoraat Geïntegreerde Complexe Zorg); de Haan, Lieuwe; Latour, Corine; Boyette, Lindy Lou

Seclusion of patients on psychiatric wards is a controversial intervention with serious safety issues for patients. Nurses have an important role in the decision to use seclusion when encountering aggressive behaviour. The aim of this thesis is to improve knowledge about the influence of nurses on the …

2021-10-06AlgemeenProefschrift

Influence of nursing staff characteristics on seclusion in acute mental health care—A prospective two-year follow-up study

Doedens, Paul (Lectoraat Geïntegreerde Complexe Zorg); ter Riet, Gerben (Faculteit Gezondheid); Vermeulen, Jentien; Boyette, Lindy-Lou; Latour, Corine (Lectoraat Geïntegreerde Complexe Zorg); de Haan, Lieuwe

Introduction Seclusion still occurs on mental health wards, despite absence of therapeutic efficacy and high risks of adverse patient effects. Literature on the effect of nursing teams, and the role of psychological characteristics in particular, on frequency of seclusion is scarce. Aim To explore the …

2021-10-01AlgemeenArtikel

Active Ingredients and Mechanisms of Change in Motivational Interviewing for Smoking Cessation in Patients With Coronary Artery Disease

Jos Dobber (Lid Lectoraat); Marjolein Snaterse; Corine Latour; Ron Peters; Gerben ter Riet; Wilma Scholte op Reimer; Lieuwe de Haan; B.K.G. (Berno) van Meijel (Lector)

Background: For patients with coronary artery disease (CAD), smoking is an important risk factor for the recurrence of a cardiovascular event. Motivational interviewing (MI) may increase the motivation of the smokers to stop smoking. Data on MI for smoking cessation in patients with CAD are limited, …

2021-06-22GezondheidArtikel

Active Ingredients and Mechanisms of Change in Motivational Interviewing for Smoking Cessation in Patients With Coronary Artery Disease: A Mixed Methods Study

Dobber, Jos; Snaterse, Marjolein; Latour, Corine (Centre Of Expertise Urban Vitality); Peters, Ron; ter Riet, Gerben (Faculteit Gezondheid); Scholte op Reimer, Wilma; de Haan, Lieuwe; van Meijel, Berno

2021-06AlgemeenArtikel

Practice of adjunctive treatments in critically ill COVID-19 patients-rational for the multicenter observational PRoAcT-COVID study in The Netherlands

Valk, Christel M. A.; Swart, Pien; Boers, Leonoor S.; Botta, Michela; Bos, Lieuwe D. J,; de Abreu, Marcelo Gama; Hol, Liselotte; Hollmann, Markus W.; Horn, Janneke; Martin-Loeches, Ignacio; Mazzinari, Guido; Myatra, Sheila N.; Nijbroek, Sunny G.; Rosenberg, Neeltje M.; Stilma, Willemke (Faculteit Gezondheid); Tsonas, Anissa M.; van der Ven, Ward H.; Neto, Ary Serpa; Schultz, Marcus J.; Paulus, Frederique

Background: Patients with coronavirus disease 2019 (COVID-19) may need hospitalization for supplemental oxygen, and some need intensive care unit (ICU) admission for escalation of care. Practice of adjunctive and supportive treatments remain uncertain and may vary widely between countries, within countries …

2021-05AlgemeenArtikel

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