Chronic nonspecific low back pain (CNSLBP) is a major problem and a leading cause of years lived with disability worldwide, with its burden expected to increase further. Disability represents a particularly important outcome in CNSLBP, as it is more strongly associated with reduced quality of life, work …

Chronische lage rugpijn (CLBP) is een veelvoorkomend en langdurig gezondheidsprobleem. CLBP gaat vaak gepaard met veranderingen in perceptie en cognitie, wat invloed kunnen hebben op hoe de omgeving wordt waargenomen. Aangezien gewichtsperceptie afhankelijk is van zowel visuele als haptische informatie, …

The aim of this thesis was to investigate the (re)organization of the primary motor cortex in people with low back pain (LBP), as well as to explore whether changes in the primary motor cortex correlate with changes in clinical tests – a motor control test, sensory tests, and pain sensitivity and modulation …

Physiotherapy is pivotal in managing musculoskeletal (MSK) conditions (1). Central to the management of MSK conditions is the biopsychosocial model, which highlights the complex relations between biological, psychological, and social factors in shaping the health and well-being of individuals with MSK …

In Chapter 2, we found that our measures to assess motor control of the trunk during seated repetitive reaching, variability (temporal and spatial) and local dynamic stability, were sufficiently reliable in single-session experiments, in a mixed group of people with and without chronic/recurrent low …

BACKGROUND: Chronic low back pain (CLBP) is the most common chronic pain condition worldwide. Currently, primary care physiotherapy is one of the main treatment options, but effects of this treatment are small. Virtual Reality (VR) could be an adjunct to physiotherapy care, due to its multimodal features. …

Background: Pain-related cognitions are associated with motor control changes in people with chronic low-back pain (CLBP). The mechanism underlying this association is unclear. We propose that perceived threat increases muscle-spindle-reflex-gains, which reduces the effect of mechanical perturbations, …

Background: Research has shown that the course of non-specific low back pain (LBP) is influenced by, among other factors, patients' self-management abilities. Therefore, clinical guidelines recommend stimulation of self-management. Enhancing patients' self-management potentially can improve patients' …

Introduction Negative pain-related cognitions are associated with persistence of low-back pain (LBP), but the mechanism underlying this association is not well understood. We propose that negative pain-related cognitions determine how threatening a motor task will be perceived, which in turn will affect …