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Oxygen Consumption with High-Flow Nasal Oxygen versus Mechanical Ventilation—An International Multicenter Observational Study in COVID–19 Patients (PROXY–COVID)

Botta, Michela; Caritg, Oriol; van Meenen, David M.P.; Pacheco, Andrés; Tsonas, Anissa M.; Mooij, Willemijn E.; Burgener, Alessia; Hehl, Tosca Manrique; Shrestha, Gentle S.; Horn, Janneke; Tuinman, Pieter R.; Paulus, Frederique (Lectoraat Critical Care); Roca, Oriol; Schultz, Marcus J.

The COVID–19 pandemic led to local oxygen shortages worldwide. To gain a better understanding of oxygen consumption with different respiratory supportive therapies, we conducted an international multicenter observational study to determine the precise amount of oxygen consumption with high-flow nasal …

2023-05AlgemeenArtikel

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

Broadening the Berlin definition of ARDS to patients receiving high-flow nasal oxygen

van der Ven, Fleur Stefanie L.I.M.; Valk, Christel M.A.; Blok, Siebe; Brouwer, Michelle G.; Go, Dai Ming; Lokhorst, Amanda; Swart, Pien; van Meenen, D. M.; Paulus, F. (Lectoraat Critical Care); Schultz, Marcus J.

Background High-flow nasal oxygen (HFNO) is increasingly used in patients with acute hypoxemic respiratory failure. It is uncertain whether a broadened Berlin definition of acute respiratory distress syndrome (ARDS), in which ARDS can be diagnosed in patients who are not receiving ventilation, results …

2023AlgemeenArtikel

Prediction of COVID-19 Infections for Municipalities in the Netherlands

Tjeerd van der Ploeg (Lid Lectoraat); Robbert Gobbens (Lector)

Abstract Background: COVID-19 was first identified in December 2019 in the city of Wuhan, China. The virus quickly spread and was declared a pandemic on March 11, 2020. After infection, symptoms such as fever, a (dry) cough, nasal congestion, and fatigue can develop. In some cases, the virus causes severe …

2022-10-20GezondheidArtikel

Short-term effect of short, intensive speech therapy on articulation and resonance in Ugandan patients with cleft (lip and) palate

Anke Luyten (Docent); H. Vermeersch; A. Hodges; K. Bettens; K. van Lierde; G. Galiwango

Objectives: The purpose of the current study was to assess the short-term effectiveness of short and intensive speech therapy provided to patients with cleft (lip and) palate (C(L)P) in terms of articulation and resonance. Methods: Five Ugandan patients (age: 7.3-19.6 years) with non-syndromic C(L)P …

2016AlgemeenArtikel

The relationship between the Nasality Severity Index 2.0 and perceptual judgments of hypernasality.

K. Bettens; Anke Luyten (Docent); F. Wuyts; M. de Bodt; K. van Lierde; Y. Maryn

PURPOSE: The Nasality Severity Index 2.0 (NSI 2.0) forms a new, multiparametric approach in the identification of hypernasality. The present study aimed to investigate the correlation between the NSI 2.0 scores and the perceptual assessment of hypernasality. METHOD: Speech samples of 35 patients, representing …

2016AlgemeenArtikel

Multimodal speech data acquisition with the use of EMA, fast-speed video cameras and a dedicated microphone array

Swiecinski, R.J.

Electromagnetic Articulography (EMA) is a technology created over two decades ago. EMA enables to acquire spatiotemporal data from sensors placed on the tongue in order to obtain information about the positioning of the tongue, its shape and dynamics during vocalizations of various sounds of human speech. …

2016AlgemeenConferentiebijdrage

Verbeteren van de huidige moleculaire snel-diagnostiek voor MRSA in het UMC Utrecht

Arjan Cornelisse (Student); Jorg Brunner (Begeleider)

Staphylococcus aureus is een bacterie die zich vooral in de neus en op de huid bevindt. Wanneer de S. aureus niet meer gevoelig is voor Methicilline, één van de gebruikelijke antibiotica, noemen we de bacterie Methicilline Resistente Staphylococcus aureus (MRSA). Er zijn in het UMC Utrecht twee verschillende …

2014-06-27AlgemeenBachelor

Verbeteren van de huidige moleculaire snel-diagnostiek voor MRSA in het UMC Utrecht

Arjan Cornelisse (Student); Jorg Brunner (Begeleider)

2014-05-21AlgemeenBachelor

Speech characteristics after palatal closure in subjects with isolated clefts: an exploration in Uganda

Anke Luyten (Docent)

Cleft lip and/or palate (CL/P) is a congenital craniofacial defect that arises on average in 1.7 per 1000 live births. This anomaly causes atypical facial appearance, hearing problems, malocclusions and speech disorders. Outcomes in terms of speech are influenced by timing of surgical cleft closure. …

2014AlgemeenProefschrift

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