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Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients—Protocol for a Delphi Study

Esmeijer, Andrea A.; Nasa, Prashant; Ntoumenopoulos, George; Battaglini, Denise; Juneja, Deven; Ball, Lorenzo; Ehrmann, Stephan; Schultz, Marcus J.; Paulus, Frederique (Lectoraat Critical Care); Stilma, Willemke (Lectoraat Geïntegreerde Complexe Zorg)

Intubated critically ill patients are susceptible to secretion accumulation because of compromised airway clearance. Various airway clearance interventions are employed to prevent complications arising from mucus retention. This Delphi study aims to collect global opinions in an international expert …

2025-08AlgemeenArtikel

Current insights on awake prone positioning in the ICU

Stilma, W. (Faculteit Gezondheid); Paulus, F. (Lectoraat Critical Care)

2025-04AlgemeenArtikel

Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe): an investigator-initiated, double-blinded, multicentre, parallel-group, randomised controlled trial in Belgium and the Netherlands

Julia L.M. Bels; Steven Thiessen; Rob J.J. van Gassel; A. Beishuizen; Ashley de Bie Dekker; Vincent Fraipont; Stoffel Lamote; Didier Ledoux; Clarissa Scheeren; Elisabeth de Waele; Arthur R.H. van Zanten; Laura Bormans-Russell; Bas C.T. van Bussel; Marlies M.J. Dictus; Tom Fivez; Ingeborg Harks; Iwan C.C. van der Horst; Joop Jonckheer; Hugues Marechal; Paul B. Massion; Ingrid Meex; Michelle C. Paulus; Martin Rinket; Susanne van Santen; Katrien Tartaglia; Adam M. Deane; Frieda Demuydt; Zudin Puthucheary; Lilian Vloet; P.J.M. Weijs; Sander M.J. van Kuijk; Marcel C.G. van de Poll; Dieter Mesotten

Increased protein provision might ameliorate muscle wasting and improve long-term outcomes in critically ill patients. The aim of the PRECISe trial was to assess whether higher enteral protein provision (ie, 2·0 g/kg per day) would improve health-related quality of life and functional outcomes in critically …

2024-08-17GezondheidArtikel

Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe)

Bels, Julia L M; Thiessen, Steven; van Gassel, Rob J J; Beishuizen, Albertus; De Bie Dekker, Ashley; Fraipont, Vincent; Lamote, Stoffel; Ledoux, Didier; Scheeren, Clarissa; De Waele, Elisabeth; van Zanten, Arthur R H; Bormans-Russell, Laura; van Bussel, Bas C T; Dictus, Marlies M J; Fivez, Tom; Harks, Ingeborg; van der Horst, Iwan C C; Jonckheer, Joop; Marechal, Hugues; Massion, Paul B; Meex, Ingrid; Paulus, Michelle C; Rinket, Martin; van Santen, Susanne; Tartaglia, Katrien; Deane, Adam M; Demuydt, Frieda; Puthucheary, Zudin; Vloet, Lilian C M; Weijs, Peter J M (Lectoraat Voeding En Beweging); van Kuijk, Sander M J; van de Poll, Marcel C G; Mesotten, Dieter

Background Increased protein provision might ameliorate muscle wasting and improve long-term outcomes in critically ill patients. The aim of the PRECISe trial was to assess whether higher enteral protein provision (ie, 2·0 g/kg per day) would improve health-related quality of life and functional outcomes …

2024-08-17AlgemeenArtikel

A Prospective, Longitudinal Study Evaluating the Efficacy of an Automated Secretion Removal Technology

Sinnige, Jante S; Karbing, Dan S; Valk, Christel M A; Schultz, Marcus J; Rees, Stephen E; Paulus, Frederique (Lectoraat Critical Care)

BACKGROUND: Endotracheal suctioning causes discomfort, is associated with adverse effects, and is resource-demanding. An artificial secretion removal method, known as an automated cough, has been developed, which applies rapid, automated deflation, and inflation of the endotracheal tube cuff during the …

2024-08AlgemeenArtikel

Effect of automated versus conventional ventilation on mechanical power of ventilation-A randomized crossover clinical trial

Buiteman-Kruizinga, Laura A.; Neto, Ary Serpa; Botta, Michela; List, Stephanie S.; de Boer, Ben H.; van Velzen, Patricia; Bühler, Philipp Karl; Wendel Garcia, Pedro D.; Schultz, Marcus J.; van der Heiden, Pim L. J.; Paulus, Frederique (Lectoraat Critical Care)

Introduction Mechanical power of ventilation, a summary parameter reflecting the energy transferred from the ventilator to the respiratory system, has associations with outcomes. INTELLiVENT–Adaptive Support Ventilation is an automated ventilation mode that changes ventilator settings according to algorithms …

2024-07AlgemeenArtikel

Effects of closed loop ventilation on ventilator settings, patient outcomes and ICU staff workloads - A systematic review

Goossen, Robin L.; Schultz, Marcus J.; Tschernko, Edda; Chew, Michelle S.; Robba, Chiara; Paulus, Frederique (Lectoraat Critical Care); Van Der Heiden, Pim L.J.; Buiteman-Kruizinga, Laura A.

BACKGROUNDLung protective ventilation is considered standard of care in the intensive care unit. However, modifying the ventilator settings can be challenging and is time consuming. Closed loop modes of ventilation are increasingly attractive for use in critically ill patients. With closed loop ventilation, …

2024-06-01AlgemeenArtikel

Open Versus Closed Suctioning in Invasively Ventilated Critically Ill Patients for Sustainability of ICU Care: A Life-Cycle Assessment Comparison

Stilma, Willemke (Urban Vitality); Esmeijer, Andrea; Paulus, Frederique (Lectoraat Critical Care); Frenzel, Tim; Touw, Hugo; Stobernack, Tim

2024-02AlgemeenArtikel

Closed-loop ventilation in COVID-19 patients with acute hypoxemic respiratory failure—A case series

Buiteman-Kruizinga, Laura A.; van der Heiden, Pim L.J.; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

Background: INTELLiVENT-adaptive support ventilation (ASV) is an automated closed-loop mode of invasive ventilation for use in critically ill patients. INTELLiVENT-ASV automatically adjusts, without the intervention of the caregiver, ventilator settings to achieve the lowest work and force of breathing. …

2024-01AlgemeenArtikel

Nursing Practice of Airway Care Interventions and Prone Positioning in ICU Patients with COVID-19-A Dutch National Survey

Esmeijer, Andrea A; van der Ven, Fleur; Koornstra, Eveline; Kuipers, Laurien; van Oosten, Paula; Swart, Pien; Valk, Christel M; Schultz, Marcus J; Paulus, Frederique (Lectoraat Critical Care); Stilma, Willemke (Faculteit Gezondheid)

Background: Airway care interventions and prone positioning are used in critically ill patients with coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU) to improve oxygenation and facilitate mucus removal. At the onset of the COVID-19 pandemic, the decision-making process regarding …

2024AlgemeenArtikel

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