HBO Kennisbank

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Zocht je misschien: production, predictive?

“Doctor, would it surprise you if there were prescribing errors in this patient's medication?” Identifying eligible patients for in-hospital pharmacotherapeutic stewardship

Rashudy F. Mahomedradja; Birgit I. Lissenberg-Witte; Kim C. E. Sigaloff; Jelle Tichelaar (Lector); Michiel A. van Agtmael

Abstract Background: Evaluating a patient's medication list is critical to reduce prescribing errors (PEs), but is a labour- and time-intensive process. Identification of patients at risk of PEs could improve the allocation of scarce time and resources, but currently available prediction tools are not …

2024-08-31GezondheidArtikel

Blood‑based biomarkers for early frailty are sex‑specific: validation of a combined in silico prediction and data‑driven approach

Jelle de Jong (Phd); Martien Jaspers (Onderzoeker); Remon Dulos (Onderzoeker); Jessica Snabel (Onderzoeker); Marjanne van der Hoek (Onderzoeker); Feike van der Leij (Lector); Robert Kleemann (Onderzoeker); Jaap Keijer (Onderzoeker); Arie Nieuwenhuizen (Onderzoeker); Anita van den Hoek (Onderzoeker); Lars Verschuren (Onderzoeker)

Kwetsbaarheid wordt gekenmerkt door verminderd fysiek functioneren en wordt bij voorkeur in een vroeg stadium gediagnosticeerd (bijvoorbeeld tijdens pre-kwetsbaarheid). Helaas ontbreken gevoelige tools die kunnen helpen bij vroege opsporing. Op bloed gebaseerde biomarkers zouden uitstekende hulpmiddelen …

2024GezondheidArtikel

Prediction of COVID-19 Infections for Municipalities in the Netherlands

Tjeerd van der Ploeg (Lid Lectoraat); Robbert Gobbens (Lector)

Abstract Background: COVID-19 was first identified in December 2019 in the city of Wuhan, China. The virus quickly spread and was declared a pandemic on March 11, 2020. After infection, symptoms such as fever, a (dry) cough, nasal congestion, and fatigue can develop. In some cases, the virus causes severe …

2022-10-20GezondheidArtikel

Lactate is associated with mortality in very old intensive care patients suffering from COVID-19

COVIP Study Group

Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have been mostly affected during the initial surge in 2020. Methods: This prospective …

2021-12-01AlgemeenArtikel

Numerical Simulation as a Precedence Method

Aflaki, A. (Ardalan) (Researcher); Esfandiari, M. (Masoud) (Researcher); Mohammadi, S (Saleh) (Associatelector)

CC-BYNatural ventilation has been used widely in buildings to deliver a healthy and comfortable indoor environment for occupants. It also reduces the consumption of energy in the built environment and dilutes the concentration of carbon dioxide. Various methods and techniques have been used to evaluate …

2021-11-01AlgemeenArtikel

Assessing Children's Fine Motor Skills With Sensor-Augmented Toys: Machine Learning Approach

Brons, Annette; de Schipper, Antoine; Mironcika, Svetlana; Toussaint, Huub; Schouten, Ben; Bakkes, Sander; Kröse, Ben

BACKGROUND: Approximately 5%-10% of elementary school children show delayed development of fine motor skills. To address these problems, detection is required. Current assessment tools are time-consuming, require a trained supervisor, and are not motivating for children. Sensor-augmented toys and machine …

2021-04AlgemeenArtikel

Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins

Raymond Pieters (Lector)

From the publisher: "Background: The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathophysiological processes and the …

2017GezondheidArtikel

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