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The Role of Burn Centers in the Treatment of Necrotizing Soft-Tissue Infections

Suijker, Jaco; Wurfbain, Lisca; Emmen, Anouk M L H; Pijpe, Anouk; Kwa, Kelly A A; van der Vlies, Cornelis H; Nieuwenhuis, Marianne K (Healthy Ageing, Allied Health Care And Nursing); van Zuijlen, Paul P M; Meij-de Vries, Annebeth

Patients with extensive and complex wounds due to Necrotizing Soft-Tissue Infections (NSTI) may be referred to a burn center. This study describes the characteristics, outcomes, as well as diagnostic challenges of these patients. Patients admitted to three hospitals with a burn center for the treatment …

2023-11-02AlgemeenArtikel

Towards precision medicine for septic patients

Bram Snoek (Student)

Sepsis is a life-threatening organ dysfunction caused by a dysregulated immune response to infection. It is the number one cause of death in the Intensive Care Unit (ICU), accounting for 6 million casualties every year. Unfortunately, all clinical trials in the last decade failed due to the highly complex …

2023-07-05Gezondheid; …Bachelor

Early high protein provision and mortality in ICU patients including those receiving continuous renal replacement therapy

van Ruijven, Isabel M.; Stapel, Sandra N.; Girbes, Armand R. J.; Weijs, Peter J. M. (Lectoraat Voeding En Beweging)

BACKGROUND: Findings on the association between early high protein provision and mortality in ICU patients are inconsistent. The relation between early high protein provision and mortality in patients receiving CRRT remains unclear. The aim was to study the association between early high protein provision …

2022-09AlgemeenArtikel

Correlation between Mottling score and peripheral skin temperature compared to the hemodynamic component of the SOFA score

Paans, Wolter (Verpleegkundige Diagnostiek); Hofman, R; Stigter, R.; Mensink, Roos; van der Veen, J.; Cox, Eline G M; Keus, Frederik; Smit, Joya; Dieperink, Willem

2022-05-10AlgemeenConferentiebijdrage

Sepsis at ICU admission does not decrease 30-day survival in very old patients

VIP1 study; Dieperink, Willem

BACKGROUND: The number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. Sepsis incidence has risen in recent years and identification of outcomes is of considerable …

2020-05-13AlgemeenArtikel

Achieving protein targets without energy overfeeding in critically ill patients: A prospective feasibility study

Looijaard, W. G.P.M.; Denneman, N.; Broens, B.; Girbes, A.R.J.; Weijs, P. J.M. (Lectoraat Voeding En Beweging); Oudemans-van Straaten, H.M.

Background & aims: High protein delivery during early critical illness is associated with lower mortality, while energy overfeeding is associated with higher mortality. Protein-to-energy ratios of traditional enteral formulae are sometimes too low to reach protein targets without energy overfeeding. …

2019-12AlgemeenArtikel

Clinical Relevance of Routinely Measured Vital Signs in Hospitalized Patients: A Systematic Review

Storm-Versloot, Marja N.; Verweij, Lotte; Lucas, Cees; Ludikhuize, Jeroen; Goslings, J. Carel; Legemate, Dink A.; Vermeulen, Hester

BACKGROUND: Conflicting evidence exists on the effectiveness of routinely measured vital signs on the early detection of increased probability of adverse events. PURPOSE: To assess the clinical relevance of routinely measured vital signs in medically and surgically hospitalized patients through a systematic …

2014-01AlgemeenArtikel

Early high protein intake is associated with low mortality and energy overfeeding with high mortality in non-septic mechanically ventilated critically ill patients

Weijs, Peter JM (Lectoraat Voeding En Beweging); Looijaard, Wilhelmus GPM; Beishuizen, Albertus; Girbes, Armand RJ; Oudemans-van Straaten, Heleen M

Abstract: INTRODUCTION: Early protein and energy feeding in critically ill patients is heavily debated and early protein feeding hardly studied.

2014AlgemeenArtikel

Endotoxemia-induced inflammation and the effect on the human brain

Lisette Schoonhoven; Mark van den Boogaard; Hans van der Hoeven; I. Fick; B. Ramakers; N. van Alfen; S. van der Werf; M. Verbeek; A. Hoedemaekers; Peter Pickkers

Effects of systemic inflammation on cerebral function are not clear, as both inflammation-induced encephalopathy as well as stress-hormone mediated alertness have been described. Experimental endotoxemia (2 ng/kg Escherichia coli lipopolysaccharide [LPS]) was induced in 15 subjects, whereas 10 served …

2010AlgemeenArtikel

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