This graduation project focuses on improving the understanding and analysis of complex business processes that are difficult to manage due to inconsistencies, lack of standardisation, and poor interoperability between systems. The project is situated in the domain of business process modelling and simulation, …

Reinforcement learning offers a promising approach for personalized, early-stage detection of behavioral events such as agitation in individuals with dementia, particularly when contextual insights from care staff are integrated. Given the scarcity and the ethical constraints of real-world agitation …

In het snel evoluerende domein van machine learning is het cruciaal om het meest geschikte model voor een bepaalde dataset te selecteren. Inzicht in de kenmerken van een dataset kan een aanzienlijke invloed hebben op de resultaten van voorspellende modellen, waardoor de studie van de eigenschappen van …

Business process modeling and system dynamics are different approaches that are used in the design and management of organizations. Both approaches are concerned with the processes in, and around, organizations with the aim to identify, design and understand their behavior as well as potential improvements. …

Business process modeling and system dynamics are different approaches that are used in the design and management of organizations. Both approaches are concerned with the processes in, and around, organizations with the aim to identify, design and understand their behavior as well as potential improvements. …

The Interoceanic corridor of Mexico stands as a pivotal infrastructure project poised to significantly enhance Mexico's national and regional economy. Anticipated to start the operations in 2025 under the auspice of the national government, this corridor represents a strategic counterpart to the Panama …

Amsterdam Airport Schiphol has faced capacity constraints, particularly during peak periods. At the security screening checkpoint, this is due to the growing number of passengers and a shortage of security staff. To improve operating performance, there is a need to integrate newer technologies that improve …

An important step towards improving performance while reducing weight and maintenance needs is the integration of composite materials into mechanical and aerospace engineering. This subject explores the many aspects of composite application, from basic material characterization to state-of-the-art advances …

Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

Despite tremendous efforts, the exact structure of SARS-CoV-2 and related betacoronaviruses remains elusive. SARS-CoV-2 envelope is a key structural component of the virion that encapsulates viral RNA. It is composed of three structural proteins, spike, membrane (M), and envelope, which interact with …