Nicotine is a well-known and highly addictive substance with complex effects on cognition, anxiety, and neurophysiology. Despite its short-term anxiolytic effects, this drug often exacerbates anxiety symptoms. It disrupts emotional regulation through its impact on the central nucleus of the amygdala …

The increasing temperature of the past years has a negative impact on the agricultural sector. This is affecting crop growth negatively, as a result from the heat and drought stress the crops are experiencing. Moreover, the experienced heat and drought stress results in erosion of the soil, causing …

Obesity is a growing global burden with numerous significant health implications, including a higher risk of developing Alzheimer’s disease (AD). This study investigates the role of obese adipose tissue on AD pathology in male APPswe/PSEN1-dE9 (APP/PSEN-1) transgenic mice, with a focus on cognitive decline, …

Brain disorders, such as Alzheimer’s disease and epilepsy have been linked to an imbalance in excitatory and inhibitory (E/I) inputs in the brain. However, the molecular mechanisms underlying E/I balance and plasticity in the brain are largely unresolved. Inhibitory synapses have a strong impact on brain …

Alzheimer's disease is a complex neurodegenerative disease and the most prevalent form of dementia. It affects every 14th person after the age of 65, thus making it a serious concern in modern society. Furthermore, currently available treatment is restricted only to symptomatic and is not highly effective. …

Over the period February 2023 to July 2023, the aim was to develop a method for the determination of endotoxin in pharmaceutical products according to GMP rules. To bring this research to a successful conclusion, the intention was to demonstrate endotoxins in pharmaceutical products using the Kinetic …

In dit onderzoek is er gekeken naar pleuravocht van een patiënt en de daarin aanwezige celtypes. Pleuravocht is een ophoping van vocht in de pleurale holtes tussen de borstkas en longen. Een vermeerdering van pleuravocht kan verschillende oorzaken hebben, zoals ontstekingen en tumoren. Om erachter te …

Autism Spectrum Disorder (ASD) is a neurobiological condition affecting about 1% of the population, characterized by repetitive behaviors, restricted interests, and communication deficiencies. While ASD has both genetic and environmental influences, the role heritable yet non genetic gastrointestinal …

In this research there was looked at the connection between the Zeta potential and the pressure sensitivity of a chloroprene dispersion in order to gain insight in dispersion stability. This was done by varying the pH and ionic strength of the chloroprene dispersion. There was also looked at whether …

Met behulp van een uitstrijkje wordt nagegaan of er een hoog risico HPV, een voorstadium van baarmoederhalskanker of baarmoederhalskanker aanwezig is. Tijdens de postmenopauze wordt het meerlagig epitheel vervangen door éénlagig eptiheel. De cellen ondergaan degeneratieve veranderingen en de diepe parabasale …