Cyclophosphamide (CPA) is a commonly used alkylating chemotherapeutic drug that targets rapidly dividing cells causing apoptosis by crosslinking DNA. While effective against neoplasms, CPA can also affect healthy immune cells. This study investigated whether a single dose of CPA alters healthy lymphoid …

BACKGROUND: Prevention programs can encourage parents to take safety measures to prevent burn injury in children under 5 years of age. The PRECEDE-PROCEED model of Green and Kreuter is a frequently used tool for stepwise development of effective prevention programs. In a previous study the first 2 phases …

One of the freedoms enjoyed by European Union (EU) citizens is the freedom of movement for workers within the EU (since 2011). This includes the rights of movement and residence for workers, the right to work in another Member State and be treated on an equal footing with nationals of that Member State. …

How do citizens, designers, policymakers, and local entrepreneurs actually work together in ways that are inclusive, sustainable, and effective? Collaboration in urban innovation is often treated as a matter of method or structure, but what happens when timelines clash, trust falters, or understanding …

Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

We are pleased to present this Book of Proceedings following the international conference “Innovating Health & Daily Life through Living Labs”, co-organised by the Dutch Empathic Environment Living Labs (DEEL Academy) and the European Network of Living Labs (ENoLL). The two-day event took place in May …

BranchOut explores how tree forks—usually treated as waste—can become valuable construction elements by leveraging their strong, continuous wood grain. Because their irregular shapes don’t fit standard building and CNC processes, the project developed new methods for harvesting, drying, and preparing …

Background Families of adolescents with severe behavior problems and an Autism Spectrum Disorder (ASD) level 1 may experience a variety of problems in their functioning. Research suggests that these problems across multiple life areas are best treated with intensive, flexible, and home-based treatment …

Background: Malnutrition and sarcopenia impact the physical health and quality of life of community-dwelling older adults. Managing these conditions requires integrating nutritional and exercise interventions delivered by professionals from diverse backgrounds. Interprofessional collaboration holds promise …

Managing dairy excreta as slurry can result in significant emissions of ammonia (NH3) and greenhouse gases (GHGs) during storage and thereafter. Additionally, slurry often has an imbalanced nitrogen (N) to phosphorus (P) ratio for crop fertilization. While various treatments exist to address emissions …