De grootste kennisbank van het HBO

Inspiratie op jouw vakgebied

Vrij toegankelijk

Terug naar zoekresultatenDeel deze publicatie

Heritable connective tissue disorders in childhood: Decreased health-related quality of life and mental health

Heritable connective tissue disorders in childhood: Decreased health-related quality of life and mental health

Samenvatting

The psychosocial consequences of growing up with Heritable Connective Tissue Disorders (HCTD) are largely unknown. We aimed to assess Health-Related Quality of Life (HRQoL) and mental health of children and adolescents with HCTD. This observational multicenter study included 126 children, aged 4–18 years, with Marfan syndrome (MFS, n = 74), Loeys–Dietz syndrome (n = 8), molecular confirmed Ehlers–Danlos syndromes (n = 15), and hypermobile Ehlers–Danlos syndrome (hEDS, n = 29). HRQoL and mental health were assessed through the parent and child-reported Child Health Questionnaires (CHQ-PF50 and CHQ-CF45, respectively) and the parent-reported Strengths and Difficulties Questionnaire. Compared with a representative general population sample, parent-reported HRQoL of the HCTD-group showed significantly decreased Physical sum scores (p 

OrganisatieHogeschool van Amsterdam
Gepubliceerd inAmerican Journal of Medical Genetics - Part A Vol. 188, Uitgave: 7, Pagina's: 2096-2109
Datum2022-07
TypeArtikel
ISSN1552-4825
DOI10.1002/ajmg.a.62750
HDL20.500.11884/d4322d56-7ea2-46f3-94e8-be8e1db3559f
TaalEngels

Op de HBO Kennisbank vind je publicaties van 26 hogescholen

De grootste kennisbank van het HBO

Inspiratie op jouw vakgebied

Vrij toegankelijk