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Distress, problems and supportive care needs of patients treated with auto- or allo-SCT

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Distress, problems and supportive care needs of patients treated with auto- or allo-SCT

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Samenvatting

Identifying factors that predict health-related quality of
life (QOL) following hematopoietic SCT, is important in
estimating patients’ abilities to adjust to the consequences
of their disease and treatment. As the studies that have
been published on this subject are scattered, the present
study aimed to systematically review prognostic factors for
health-related QOL after auto- and allo-SCT in hematological
malignancies. A systematic, computerized search
in Medline, EMBASE, PsycINFO and the Cochrane
Library was conducted from 2002 to June 2010. The
methodological quality of the studies was assessed using an
adaptation of Hayden’s criteria list. Qualitative data
synthesis was performed to determine the strength of the
scientific evidence. In all, 35 studies fulfilled the selection
criteria. Strong–moderate evidence was found for GVHD,
conditioning regimen, being female, younger age, receiving
less social support and pre-transplant psychological
distress as predictors of various aspects of health-related
QOL following hematopoietic SCT. The results of this
review may help transplant teams in selecting patients at
risk for experiencing a diminished health-related QOL
following hematopoietic SCT. Follow-up treatment can be
provided in order to promote QOL.

Toon meer
OrganisatieHogeschool Inholland
Opleiding
InstituutDomein Gezondheid, Sport en Welzijn
LectoraatGGZ-Verpleegkunde
Gepubliceerd inBone Marrow Transplantation Uitgave: 49, Pagina's: 292-298
Datum2012-07-04
TypeArtikel
TaalEngels

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