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Zocht je misschien: metabolic?

Evidence for effect of l-serine, a novel therapy for GRIN2B-related neurodevelopmental disorder.

B. den Hollander; A.R.J. Veenvliet; Marieke Lindenschot; P. van Essen; G. Peters; A. Santos-Gómez; M. Olivella; X. Altafaj; M.M. Brands; B.A.W. Jacobs; C.D. van Karnebeek

RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-function (LoF) variants in GRIN2B, resulting in dysfunction of the GluN2B subunit-containing N-methyl-d-aspartate receptor (NMDAR). Recently, in vitro experiments showed that …

2023AlgemeenArtikel

Dietary counseling on malnutrition:

Barkmeijer, Alyanne; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Lamerichs, Joyce; te Molder, Hedwig

Rationale: In this study, we aimed to explore how dietitians’ history-taking questions function during dietary counseling of clients with malnutrition (risk). Fruitful functioning of history-taking questions during the problem identification phase is crucial for dietitians to develop a client-centered …

2022-09-04Gezondheid; …Conferentiebijdrage

Towards effective dietary counseling:

Barkmeijer, Alyanne; te Molder, Hedwig; Janssen, Mariam; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing)

Rationale: In this scoping review we aimed to identify and map available evidence concerning counseling strategies that contribute to effective dietary counseling. Dietary counseling, as component of dietary treatment, is important to empower clients in achieving dietary treatment goals. Methods: Following …

2022-09-04Gezondheid; …Conferentiebijdrage

A foundation for dietitians to effectively carry out dietary counseling

Barkmeijer, Alyanne; te Molder, Hedwig; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Janssen, Mariam

2022-09-04Gezondheid; …Conferentiebijdrage

History-taking questions not only elicit answers with information, but also evoke client's self-presentation

Barkmeijer, Alyanne; te Molder, Hedwig; Lamerichs, Joyce; Jager-Wittenaar, Harriët (Healthy Ageing, Allied Health Care And Nursing)

2022-09-04Gezondheid; …Conferentiebijdrage

Severity Of Glim-Defined Malnutrition In The Dutch Primary Care Setting At The Initial Dietitian Consult

Sealy, Martine (Malnutrition And Healthy Ageing); Jager-Wittenaar, Harriët (Healthy Ageing, Allied Health Care And Nursing); Mulder, Petra

2022-09Gezondheid; …Conferentiebijdrage

Inter-individual variation in chlorpyrifos toxicokinetics characterized by physiologically based kinetic (PBK) and Monte Carlo simulation comparing human liver microsome and Supersome™ cytochromes P450 (CYP)-specific kinetic data as model input

Zhao, S.; Wesseling, S.; Rietjens, I.M.C.M.; Strikwold, M. (Lector)

The present study compares two approaches to evaluate the effects of inter-individual differences in the biotransformation of chlorpyrifos (CPF) on the sensitivity towards in vivo red blood cell (RBC) acetylcholinesterase (AChE) inhibition and to calculate a chemical-specific adjustment factor (CSAF) …

2022-03-16GezondheidArtikel

The association between gastrointestinal injury, complaints, and food intake in 60-km ultramarathon runners.

N.F.J. van Venrooij; F.C. Wardenaar; D. Hoogervorst; J.M.G. Senden; Jan-Willem van Dijk; Kristin Jonvik

We aimed to assess the association between gastrointestinal (GI) injury, complaints, and food intake in 60-km ultramarathon runners. Thirty-three ultramarathon runners provided pre- and post-race blood samples for assessment of GI injury by intestinal fatty-acid binding protein (I-FABP), and inflammatory …

2022AlgemeenArtikel

The effect of SMPD4 absence on mitosis and neuronal progenitor cell number

Marta Sério Ferreira (Student); Kas Wannee (Docent); José de Winter (Docent); Daphne Smits (Begeleider)

SMPD4 is a neutral sphingomyelinase that plays an important role in sphingolipid metabolism. Sphingolipids are a family of lipid molecules abundantly present in the brain where they play an important role in the brain development and function due to their essential cellular role as structural components …

2021-06-21Natuur & LandbouwBachelor

Architecture On Demand

Koen Huijs (Student)

A theoretical and cultural framework, derived from Japanese sources and work by Lebbeus Woods, leads to a vision and design promoting a neo-metabolism, an architecture subjected to its users. De-territorialization and translucency join in creating a collective environment with private units, assembled …

2021-05-23Taal, Cultuur & KunstenMaster

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