Cyclophosphamide (CPA) is a commonly used alkylating chemotherapeutic drug that targets rapidly dividing cells causing apoptosis by crosslinking DNA. While effective against neoplasms, CPA can also affect healthy immune cells. This study investigated whether a single dose of CPA alters healthy lymphoid …

lorio, the newly opened restaurant at The Charles Hotel in Munich, is currently faced with the challenge of not meeting its targeted average spend per guest. As a result of a drastic reduction in seating capacity – from 35 to 16 tables – due to a complete restaurant design, management is under pressure …

Background The global nursing shortages exacerbated by the COVID-19 pandemic necessitated a drastic reorganization in nursing practices. Work routines, the composition of teams and subsequently mundane nursing practices were all altered to sustain the accessibility and quality of care. These dramatic …

Background The global nursing shortages exacerbated by the COVID-19 pandemic necessitated a drastic reorganization in nursing practices. Work routines, the composition of teams and subsequently mundane nursing practices were all altered to sustain the accessibility and quality of care. These dramatic …

Densely populated areas are major sources of air, soil and water pollution. Agriculture, manufacturing, consumer households and road traffic all have their share. This is particularly true for the country featured in this paper: the Netherlands. Continuous pollution of the air and soil manifests itself …

Dairy cooperatives have been around in the Netherlands for more than 130 years (Bijman, 2018). A growing European economy and growing demand for dairy products offered opportunities for further growth (Bijman, 2018). As the technological development in dairy processing evolved, cooperatives continued …

Online food shopping has been a business model on the rise for some time. However, significant increased growth in consumers using e-commerce to purchase food has never been so high as that recorded in 2020. During this year, the world was hit by the pandemic. Governments from countries around the world …

The European Migrant Crisis of 2015 has brought drastic challenges on national and European levels in regard to the reception of asylum seekers and in sharing responsibility among member states. Many eastern and southern member states, however, felt the necessity to cope with the consequences of the …

Paris Charles de Gaulle Airport was the second European airport in terms of traffic in 2019, having transported 76.2 million passengers. Its large infrastructures include four runways, a large taxiway network, and 298 aircraft parking stands (131 contact) among three terminals. With the current pandemic …

The challenge of sustainable development requires cities to aim for drastic improvements in the systems that support its vital functions. Innovating these systems can be extremely hard, and might take lots of time. A transparent and democratic strategy is important to guarantee support for change. Such …