Tutorials play a crucial role in serious game development as they provide new users with clear information and guide them through the fundamental interactions in the experience, assisting with the novelty effect. This report discusses the design and development of a modular tutorial tool created for …

Many have suggested that AI-based interventions could enhance learning by personalization, improving teacher effectiveness, or by optimizing educational processes. However, they could also have unintended or unexpected side-effects, such as undermining learning by enabling procrastination, or reducing …

Background and aim: Moderate preterm (MP) birth is associated with an increased risk of developmental problems. However, post-discharge support for this group is scarce. The aim of this study was to evaluate the feasibility of a post-discharge parenting program (TOP program) for MP infants. Three feasibility …

Over the last four months I have been working at Mitsubishi Turbocharger and Engine Europe B.V. (MTEE) in Almere, Netherlands. As part of my Bachelor’s thesis assignment, I was given the task to investigate the working principle of Helmholtz resonators and evaluate the factors influencing the sound …

This study sought to comprehensively examine the complex relationship between de-icing substances and asphalt pavement, with an emphasis on understanding how freeze-thaw cycles and various deicers affect infrastructure performance and longevity. The primary focus was centered around strengthening understanding …

Purpose Cancer-related cognitive impairment (CRCI) following chemotherapy is commonly reported in breast cancer survivors, even years after treatment. Data from preclinical studies suggest that exercise during chemotherapy may prevent or diminish cognitive problems; however, clinical data are scarce. …

Objective. After laryngectomy, the breathing resistance of heat and moisture exchangers may limit exercise capacity. Breathing gas analysis during cardiopulmonary exercise testing is not possible using regular masks. This study tested the feasibility of cardiopulmonary exercise testing with a heat and …

Background: Dermoscopy is known to increase the diagnostic accuracy of pigmented skin lesions (PSLs) when used by trained professionals. The effect of dermoscopy training on the diagnostic ability of dermal therapists (DTs) has not been studied so far. Objectives: This study aimed to investigate whether …

Post-earthquake structural damage shows that out-of-plane wall collapse is one of the most prevalent failure mechanisms in unreinforced masonry (URM) buildings. This issue is particularly critical in Groningen, a province located in the northern part of the Netherlands, where low-intensity ground shaking …

Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …