Background: Immune-related adverse drug reactions (ADRs) to immunotherapy agents have been associated with beneficial clinical outcomes in oncology. Viscum album L. (VA, European mistletoe) is frequently used as an immunomodulatory agent alongside conventional cancer treatment in Europe. VA has been …

Design-based inquiries into the networked products of the Internet of Things (IoT) lack a coherent understanding of the effect of such products on society. This paper proposes a new taxonomy for networked products, which would allow articulation on their current state and future, and provide insights …

From the website of the publisher: "Background Nocturnal sialorrhea is one of the most frequent adverse events in clozapine treatment. Symptomatic management of sialorrhea usually consists of off-label treatment with anticholinergic agents. The aim of the current study is to evaluate the efficacy and …

from the repository of Utrecht University: "OBJECTIVES: Antipsychotic drugs are frequently prescribed to elderly patients, but they are associated with serious adverse effects. The objective of the current study was to investigate the association between use of antipsychotics by elderly women and the …

Background: Guidance of patients treated with antidepressants is paramount for successful therapy. The aim was to assess patients’ needs and suggestions for improvement of guidance by physicians and pharmacists during second generation antidepressant (SGA) therapy. Methods: Five focus group discussions …

This article is about the effect of local tailored interventions to counter (violent) extremism, and therefore contributes to the academic and policy debates. It focusses on local, professional perspectives on person-specific interventions utilising a Dutch case study as the basis. The interventions …

Cairo. Home to twenty million people, bursting at the seams. An archipelago of planned and unplanned districts. How should this metropolis prepare for future growth? ‘Delta Strikes Back’ focuses on the rapidly urbanising agricultural landscape within the Nile Delta. Environmental pressure, ‘water wars’ …

Biofilm is an important virulence factor in Pseudomonas aeruginosa and has a substantial role in antibiotic resistance and chronic burn wound infections. New therapeutic agents against P. aeruginosa, degrading biofilms in burn wounds and improving the efficacy of current antimicrobial agents, are required. …

Agent-based modeling is used for simulating the actions and interactions of autonomous entities aiming to assessing their effects on the system as a whole. At an abstract level, an agent-based model (ABM) is a representation of the many simple agents and interactions among them. The decision making of …

From the article: "The term Internet of Things (IoT) is used for situations where one or more devices are connected to a network or possibly the Internet. Most studies focus on the possibilities that arise when a device is capable to share its data with other devices or humans. In this study, the focus …