Most arguments in favor of command line versus graphical user interface (GUI) computing are flawed by system administrator Platonism. A command like "cp test.txt /mnt/disk" is, however, not a single bit closer to a hypothetic "truth" of the machine than dragging an icon of the file.txt with a mouse pointer …

The analysis of regulatory regions in genome sequences is strongly based on the detection of potential transcription factor binding sites. The preferred models for representation of transcription factor binding specificity have been termed position-specific scoring matrices. JASPAR is an open-access …