Traditional non-linear models offer Dutch municipalities limited insight into the social behaviour of local stakeholders, even though this behaviour largely determines the success of policies in complex sociotechnical systems. This study addresses the following research question: “How can an agent-based …

Awareness of climate change and stricter emission regulations have accelerated the search for sustainable energy solutions. A central goal is carbon-neutral energy use, minimizing greenhouse gas emissions while ensuring reliable energy supply. In applications with limited grid access—such as festivals, …

BACKGROUND: Sarcopenic obesity (SO) is a clinical condition defined by the coexistence of high body fat mass and low muscle function and mass, which increases the risk of adverse health outcomes, including disability and mortality. Early detection and frequent monitoring of SO are essential for preventive …

The gram-positive bacterium Bacillus subtilis is widely used for enzyme production, especially due to its superior protein secretion capacity. In this study, we have investigated how efficient transcriptome analysis can identify general and protein-specific secretion stress. For this, we constructed …

This paper explores the relationship between Circular Economy (CE) and Environmental, Social, and Governance (ESG) frameworks—a connection that remains ambiguous in both academic literature and practical application. This lack of clarity hinders corporate accountability and progress toward sustainability …

Introduction: Self-management for patients with chronic obstructive pulmonary disease (COPD) is essential in preventing relapse and rehospitalization. This study aimed to adapt a self-management-supporting digital monitoring system that was designed for COPD patients at home, to older patients with COPD …

While there is much focus on interventions to foster ethical reflection in the design process of AI, there is less focus on fostering ethical reflection for (end)users. Yet, with the rise of genAI, AI technologies are no longer confined to expert users; non-experts are widely using these technologies. …

The focus of this deep-dive, facilitated by the ESF-staff, is on digital tooling to design PEDs, to predict and control the energy flows in a PED and to monitor PEDs and evaluate their effectiveness. All this to accelarete PED development in relation to the Mission of 100 climate-neutral and smart cities …

BACKGROUND: The mainstay of colorectal cancer care is surgical resection, which carries a significant risk of complications. Efforts to improve outcomes have recently focused on intensive multimodal prehabilitation programs to better prepare patients for surgery, which make the perioperative process …

In the Netherlands, almost everyone has an image of 1930s neighborhoods, post-war neighborhoods, and Vinex locations. That is very different for the neighborhoods with social housing apartments from the 1970s and 1980s. They are forgotten, hardly known, even professionally. And that is a problem because …