RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-function (LoF) variants in GRIN2B, resulting in dysfunction of the GluN2B subunit-containing N-methyl-d-aspartate receptor (NMDAR). Recently, in vitro experiments showed that …

Aware of the consequences of their inactive lifestyles, many people still struggle to integrate enough physical activity into their busy lives. Interventions that nudge to reinforce existing active behaviour seem therefore more likely to be effective than those adding an activity to daily routines. To …

Aware of the consequences of their inactive lifestyles, many people still struggle to integrate enough physical activity into their busy lives. Interventions that nudge to reinforce existing active behaviour seem therefore more likely to be effective than those adding an activity to daily routines. To …

Background Following an ecological framework, the aim of this study was to highlight the way adolescents invested their time in opportunities to engage in moderate to vigorous physical activity (MVPA) according to whether they were profiled as more or less active. This study’s innovation lies in the …

Background: Children with asthma can decrease the impact of their disease by improving their physical activity (PA). However, health care providers lack interventions for children with asthma that effectively increase their PA levels and achieve behavior change. A technology-supported approach can positively …

Deployment and management of environmental infrastructures, such as charging infrastructure for Electric Vehicles (EV), is a challenging task. For policy makers, it is particularly difficult to estimate the capacity of current deployed public charging infrastructure for a given EV user population. While …

Animal burrows create discontinuities on the body of earthen levees that under certain circumstances can threaten their structural integrity through hydraulic alteration and surface erosion. Although it is a virtually established fact that discontinuities can undermine the structural integrity of levees, …

Research suggests that muscle power is a more critical determinant of physical functioning in older adults than muscle strength. The objective of this study was to systematically review the literature on the effect of power training compared to strength training in older adults on tests for muscle power, …

Achtergrond Fundamentele Motorische Vaardigheden (FMV) zijn belangrijke bouwstenen voor de sportdeelname en levenslange lichamelijke activiteit van kinderen. In het afgelopen decennium hebben verschillende internationale onderzoeken vertragingen in de ontwikkeling van FMV gemeld. Om een ​​beter inzicht …

From 17-21 May ClimateCafé Zwolle will be held on the topic of drought. We will execute full scale tests in the Zwolle region (municipalities of Zwolle, Meppel, Deventer, Raalte and Westerveld) and gather more information on functioning of climate solutions, biodiversity and stakeholder participation. …