Many origin of life theories argue that molecular self-organization explains the spontaneous emergence of structural and dynamical constraints. However, the preservation of these constraints over time is not well-explained because of the self-undermining and self-limiting nature of these same processes. …

The use of robots as educational tools provides a stimulating environment for students. Some robotics competitions focus on primary and secondary school aged children, and serve as motivation for students to get involved in educational robotics activities. Although very appealing, many students cannot …

OBJECTIVES: To demonstrate that novice dosimetry planners efficiently create clinically acceptable IMRT plans for head and neck cancer (HNC) patients using a commercially available multicriteria optimization (MCO) system. METHODS: Twenty HNC patients were enrolled in this in-silico comparative planning …

Many research projects have assessed the possibility and effectiveness of implementing games as health interventions. Recent literature shows generally positive results in specific case studies. However we acknowledged that research projects in this field regularly seem to disregard the connection to …

Simulation transparency is becoming more crucial in the decision making process when quantitative computer tools are used to justify some strategies.

OBJECTIVE: To determine the value of training for the Emergency Management of Severe Burns (EMSB) for medical and nursing staff working in emergency care as measured by their performance in a simulated burn incident online program. METHODS: An Internet-based questionnaire, which included a simulated …

Training systems with intelligent virtual agents provide an effective means to train people for complex, dynamic tasks like crisis management or firefighting. Virtual agents provide more adequate behavior and explanations if they not only take their own goals and beliefs into account, but also the assumed …

Genomics has multiplied the number of targets for new therapeutic interventions, but this has not yet lead to a marked increase of pharma pipeline outputs. The complexity of protein function in higher order biological systems is often underestimated. Translation from in vitro and in vivo results to the …