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Effect of mechanical power on mortality in invasively ventilated ICU patients without the acute respiratory distress syndrome

van Meenen, David M.P.; Algera, Anna Geke; Schuijt, Michiel T.U.; Simonis, Fabienne D.; van der Hoeven, Sophia M.; Neto, Ary Serpa; Abreu, Marcelo Gama de; Pelosi, Paolo; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

BACKGROUND The mechanical power of ventilation (MP) has an association with outcome in invasively ventilated patients with the acute respiratory distress syndrome (ARDS). Whether a similar association exists in invasively ventilated patients without ARDS is less certain. OBJECTIVE To investigate the …

2023-01AlgemeenArtikel

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

Patient outcomes before and after implementation of a selective pre-hospital spinal immobilization protocol

Otto van de Breevaart (Onderzoeker); Nancy van de Waarden (Onderzoeker); Lisette Schoonhoven (Onderzoeker); Wietske Blom-Ham (Onderzoeker); Niels Schep (Onderzoeker)

Background: A new selective preventive spinal immobilization (PSI) protocol was introduced in the Netherlands. This may have led to an increase in non-immobilized spinal fractures (NISFs) and consequently adverse patient outcomes. Aim: A pilot study was conducted to describe the adverse patient outcomes …

2023GezondheidArtikel

Broadening the Berlin definition of ARDS to patients receiving high-flow nasal oxygen

van der Ven, Fleur Stefanie L.I.M.; Valk, Christel M.A.; Blok, Siebe; Brouwer, Michelle G.; Go, Dai Ming; Lokhorst, Amanda; Swart, Pien; van Meenen, D. M.; Paulus, F. (Lectoraat Critical Care); Schultz, Marcus J.

Background High-flow nasal oxygen (HFNO) is increasingly used in patients with acute hypoxemic respiratory failure. It is uncertain whether a broadened Berlin definition of acute respiratory distress syndrome (ARDS), in which ARDS can be diagnosed in patients who are not receiving ventilation, results …

2023AlgemeenArtikel

Effect of lung ultrasound-guided fluid deresuscitation on duration of ventilation in intensive care unit patients (CONFIDENCE)

Blok, Siebe G.; Mousa, Amne; Brouwer, Michelle G.; de Grooth, Harm-Jan; Neto, Ary Serpa; Blans, Michiel J.; den Boer, Sylvia; Dormans, Tom; Endeman, Henrik; Roeleveld, Timo; Scholten, Harm; van Slobbe-Bijlsma, Eline R.; Scholten, Erik; Touw, Hugo; van der Ven, Fleur Stefanie L. I. M.; Wils, Evert-Jan; van Westerloo, David J.; Heunks, Leo M. A.; Schultz, Marcus J.; Paulus, Frederique (Lectoraat Critical Care); Tuinman, Pieter R.

Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation and length of intensive care unit (ICU) stay. However, optimal …

2023AlgemeenArtikel

Measure to improve: is there a patient-acuity measurement tool suitable for use in maternity service provision in the Netherlands? A systematic review

D.J. Cronie; A.N. Rosman; R. de Vries

Background and Aims It is difficult to overestimate the importance of safe staffing levels within the context of effective, quality healthcare. Poor staffing has been cited as a contributory factor in the number of unnecessary hospital deaths. This is particularly so in maternity care, where poor staffing …

2022-10-11GezondheidArtikel

Early high protein provision and mortality in ICU patients including those receiving continuous renal replacement therapy

van Ruijven, Isabel M.; Stapel, Sandra N.; Girbes, Armand R. J.; Weijs, Peter J. M. (Lectoraat Voeding En Beweging)

BACKGROUND: Findings on the association between early high protein provision and mortality in ICU patients are inconsistent. The relation between early high protein provision and mortality in patients receiving CRRT remains unclear. The aim was to study the association between early high protein provision …

2022-09AlgemeenArtikel

Effects of a transitional care programme on medication adherence in an older cardiac population

Daliri, Sara; Kooij, Marcel J.; Scholte op Reimer, Wilma J. M.; ter Riet, Gerben (Lectoraat Voeding En Beweging); Jepma, Patricia; Verweij, Lotte; Peters, Ron J. G.; Buurman, Bianca M.; Karapinar-Çarkit, Fatma

Aims Medication non-adherence post-discharge is common among patients, especially those suffering from chronic medical conditions, and contributes to hospital admissions and mortality. This study aimed to evaluate the effect of the Cardiac Care Bridge (CCB) intervention on medication adherence post-discharge. …

2022-03AlgemeenArtikel

Acute burn care in resource-limited settings

Hendriks, T.C.C.; Botman, M.; Binnerts, J J; Mtui, G.S.; Nuwass, E.Q.; Meij-de Vries, A.; Winters, H.A.H.; Nieuwenhuis, M.K. (Healthy Ageing, Allied Health Care And Nursing); van Zuilen, P.P.M.

Background: Only a few papers are published on the safety and effectiveness of acute burn care in low-income countries. A cohort study was therefore carried out to determine such outcomes. Methods: The study was conducted in a rural Tanzanian hospital in 2017-2018. All patients admitted with burns were …

2022-01-26AlgemeenArtikel

Comparison of the prevalence of 21 GLIM phenotypic and etiologic criteria combinations and association with 30-day outcomes in people with cancer: A retrospective observational study.

N Kiss; B. Steer; J Loeliger; R. Alizadehsani; L. Edbrooke; I Deftereos; E. Laing; A. Khosravi; Marian de van der Schueren

BACKGROUND & AIMS: The Global Leadership Initiative on Malnutrition (GLIM) criteria require validation in various clinical populations. This study determined the prevalence of malnutrition in people with cancer using all possible diagnostic combinations of GLIM etiologic and phenotypic criteria and determined …

2022AlgemeenArtikel

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