The critical care community still has mixed feelings when considering the optimal nutrition of intensive care unit (ICU) patients, which is understandable as randomized controlled trials have not been very helpful in improving clinical practice. There have been no randomized controlled trials (RCTs) …

From the thesis: "Summary Metabolic diseases that are characterized by a disturbance in energy balance because of feeding behavior, such as obesity and anorexia are known to be a world-wide problem. A better understanding in central regulation of energy intake and metabolism could give more insight in …

Introduction: Throughout life, a patient with severe haemophilia is confronted with many treatment-related challenges. Insight into self-management and non-adherence could improve the quality of care for these patients. The aim of this study was to provide an overview of the current evidence on self-management …

Prophylactic replacement therapy is the cornerstone of treatment in severe haemophilia. Regular infusions with clotting factor concentrate have been proven effective to prevent bleeding, subsequent (joint) damage, and positively affect the impact of haemophilia on daily life [1]. Patients or parents …

Purpose: The aims of this study were to investigate how a variety of research methods is commonly employed to study technology and practitioner cognition. User-interface issues with infusion pumps were selected as a case because of its relevance to patient safety. Methods: Starting from a Cognitive …

PRRT is a method of treatment that is used for a variety of diseases. In this method of treatment patient are infused with a radiopharmaceutical. This radiopharmaceutical will deliver a radiation dose to the specific targeted organ. However, due to infusion in the bloodstream other organs will also sustain …

Ghrelin, a peptide predominantly produced by the stomach [1], appears to play an important role in the regulation of food intake. Intravenous infusion of ghrelin stimulates food intake and enhances appetite in humans [2]. In addition, plasma ghrelin concentrations rise gradually before a meal and decrease …