Since Factor H is the main regulator of the complement system, any dysregulation may result in either uncontrolled complement activation or inhibition. Auto-antibodies against Factor H inhibit the protective function of Factor H on host cells, which are now sensitive for complement activation. It is …

Objective: To understand inactivity and relapse from PA, and to develop theory-based behaviour change strategies to stimulate and support maintenance of PA. Methods: We conducted a literature search to explore barriers to PA. Social cognitive theories and empirical evidence were evaluated and guided …

A baseline study was performed to characterize the stormwater quality from the upstream roofs and road areas. Results showed variations in stormwater quality. This may inhibit single-step treatment performance. Therefore, a ‘treatment train’ of several SUDS measures was developed in order to achieve …

Although creativity is often seen as requiring spontaneity and flexibility, recent work suggests that there is creative potential in a structured and systematic approach as well. In a series of four experiments, we show that when Personal Need for Structure (PNS) is high, either chronic (Study 1) or …

Let us assume that organizations want to blossom in order to achieve their goals in the best possible manner. Why, then, does this fail to occur so often, despite major efforts in HRM such as education, development of competencies, and management training? This article deals with learning obstacles in …

Verifying information is one of the core activities of journalism. However, recent research shows that many stories derive from unchecked information from news agencies and PR material. That being said, reporters who do not use this pre-packaged material, but who instead produce original stories based …

Patients in hospitals and nursing homes are at risk of the development of, often preventable, adverse events (AEs), which threaten patient safety. Guidelines for prevention of many types of AEs are available, however, compliance with these guidelines appears to be lacking. Besides general barriers that …

Bisphosphonates (BPs) are widely used in the treatment of osteolytic bone disease associated with multiple myeloma, and have been demonstrated to exert antitumor effects both in vitro and in vivo. However, the precise molecular mechanisms involved in the direct antitumor effects of BPs in vitro are not …