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Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU

SUP-ICU trial group

BACKGROUND: Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear. METHODS: In this European, multicenter, parallel-group, blinded trial, we randomly assigned adults who had been admitted to the ICU …

2018-12-06AlgemeenArtikel

De-implementation strategy to Reduce the Inappropriate use of urinary and intravenous CATheters study protocol for the RICAT-study

Laan, Bart J.; Spijkerman, Ingrid J. B.; Godfried, Mieke H.; Pasmooij, Berend C.; Maaskant, Jolanda M.; Borgert, Marjon J.; Opmeer, Brent C.; Vos, Margreet C.; Geerlings, Suzanne E.

BACKGROUND: Urinary and (peripheral and central) intravenous catheters are widely used in hospitalized patients. However, up to 56% of the catheters do not have an appropriate indication and some serious complications with the use of these catheters can occur. The main objective of our quality improvement …

2017-01-10AlgemeenArtikel

Safe and effective nursing shift handover with NURSEPASS

Smeulers, Marian; Dolman, Christine D.; Atema, Danielle; van Dieren, Susan; Maaskant, Jolanda M.; Vermeulen, Hester

AIM: Implementation of a locally developed evidence based nursing shift handover blueprint with a bedside-safety-check to determine the effect size on quality of handover. METHODS: A mixed methods design with: (1) an interrupted time series analysis to determine the effect on handover quality in six …

2016-11AlgemeenArtikel

Review on pharmacological pain management in trauma patients in (pre-hospital) emergency medicine in the Netherlands

BM Dijkstra; Sivera Berben; RTM van Dongen; L Schoonhoven

Pain is one of the main complaints of trauma patients in (pre-hospital) emergency medicine. Significant deficiencies in pain management in emergency medicine have been identified. No evidence-based protocols or guidelines have been developed so far, addressing effectiveness and safety issues, taking …

2014AlgemeenArtikel

Intravenous pamidronate treatment in children with moderate-to-severe osteogenesis imperfecta started under three years of age

Alcausin, M.B.; Briody, J.; Pacey, V.; Ault, J.; McQuade, M.; Bridge, C.; Engelbert, R.H.H. (Faculteit Gezondheid); Sillence, D.O.; Munns, C.F.

OBJECTIVE: Evaluate clinical outcome of early cyclic intravenous pamidronate treatment in children with moderate-to-severe osteogenesis imperfecta (OI), commenced before three years of age. METHODS: A retrospective review of 17 patients with moderate-to-severe OI. Development, anthropometry, fracture …

2013-07AlgemeenArtikel

Accuracy of burn size assessment prior to arrival in Dutch burn centres and its consequences in children

Baartmans, M G A; van Baar, M E; Boxma, H; Dokter, J; Tibboel, D; Nieuwenhuis, M K (Functional Recovery And Quality Of Life After Burns)

BACKGROUND: Total body surface area (TBSA) burned, expressed as percentage is one of the most important aspects of the initial care of a burn victim. It determines whether transfer to a burn centre is necessary as well as the need for, and amount of, intravenous fluid resuscitation. Numerous studies, …

2012-09-01Gezondheid; …Artikel

Postprandial ghrelin responses are associated with the intermeal interval in time-blinded normal weight men, but not in obese men

G. Stafleu; W. Blom; Gertjan Schaafsma; A. Lluch; Aart-Jan de Graaf; H.F.J. Hendriks

Ghrelin, a peptide predominantly produced by the stomach [1], appears to play an important role in the regulation of food intake. Intravenous infusion of ghrelin stimulates food intake and enhances appetite in humans [2]. In addition, plasma ghrelin concentrations rise gradually before a meal and decrease …

2009AlgemeenArtikel

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