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Oxygen Consumption with High-Flow Nasal Oxygen versus Mechanical Ventilation—An International Multicenter Observational Study in COVID–19 Patients (PROXY–COVID)

Botta, Michela; Caritg, Oriol; van Meenen, David M.P.; Pacheco, Andrés; Tsonas, Anissa M.; Mooij, Willemijn E.; Burgener, Alessia; Hehl, Tosca Manrique; Shrestha, Gentle S.; Horn, Janneke; Tuinman, Pieter R.; Paulus, Frederique (Lectoraat Critical Care); Roca, Oriol; Schultz, Marcus J.

The COVID–19 pandemic led to local oxygen shortages worldwide. To gain a better understanding of oxygen consumption with different respiratory supportive therapies, we conducted an international multicenter observational study to determine the precise amount of oxygen consumption with high-flow nasal …

2023-05AlgemeenArtikel

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

Broadening the Berlin definition of ARDS to patients receiving high-flow nasal oxygen

van der Ven, Fleur Stefanie L.I.M.; Valk, Christel M.A.; Blok, Siebe; Brouwer, Michelle G.; Go, Dai Ming; Lokhorst, Amanda; Swart, Pien; van Meenen, D. M.; Paulus, F. (Lectoraat Critical Care); Schultz, Marcus J.

Background High-flow nasal oxygen (HFNO) is increasingly used in patients with acute hypoxemic respiratory failure. It is uncertain whether a broadened Berlin definition of acute respiratory distress syndrome (ARDS), in which ARDS can be diagnosed in patients who are not receiving ventilation, results …

2023AlgemeenArtikel

Prediction of COVID-19 Infections for Municipalities in the Netherlands

Tjeerd van der Ploeg (Lid Lectoraat); Robbert Gobbens (Lector)

Abstract Background: COVID-19 was first identified in December 2019 in the city of Wuhan, China. The virus quickly spread and was declared a pandemic on March 11, 2020. After infection, symptoms such as fever, a (dry) cough, nasal congestion, and fatigue can develop. In some cases, the virus causes severe …

2022-10-20GezondheidArtikel

Verbeteren van de huidige moleculaire snel-diagnostiek voor MRSA in het UMC Utrecht

Arjan Cornelisse (Student); Jorg Brunner (Begeleider)

Staphylococcus aureus is een bacterie die zich vooral in de neus en op de huid bevindt. Wanneer de S. aureus niet meer gevoelig is voor Methicilline, één van de gebruikelijke antibiotica, noemen we de bacterie Methicilline Resistente Staphylococcus aureus (MRSA). Er zijn in het UMC Utrecht twee verschillende …

2014-06-27AlgemeenBachelor

Verbeteren van de huidige moleculaire snel-diagnostiek voor MRSA in het UMC Utrecht

Arjan Cornelisse (Student); Jorg Brunner (Begeleider)

2014-05-21AlgemeenBachelor

The effect of nasal breathing on amateur runners

Orsolya Hegyi (Student); Chris Burtin (Begeleider)

Background: Nasal breathing is a commonly used technique among runners. However, the scientific research available on the topic is limited. The aim of this study was to investigate the effect of nasal breathing on runners' posture, perceived exertion and the effect of practice. Method: The participants, …

2013GezondheidBachelor

The role of nasal carriage in Staphylococcus aureus burn wound colonization

Kooistra-Smid, Mirjam; Nieuwenhuis, Marianne (Functional Recovery And Quality Of Life After Burns); Van Belkum, Alex; Verbrugh, Henri

Thermal injury destroys the physical skin barrier that normally prevents invasion of microorganisms. This and concomitant depression of local and systemic host cellular and humoral immune responses are important factors that contribute to colonization and infection of the burn wound. One of the most …

2009-10-01Gezondheid; …Artikel

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