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Stratified exercise therapy does not improve outcomes compared with usual exercise therapy in people with knee osteoarthritis (OCTOPuS study): a cluster randomised trial.

J. Knoop; J Dekker; J.M. van Dongen; M van der Leeden; M. de Rooij; W.F. Peter; W. de Joode; L. van Bodegom-Vos; N. Lopuhaä; K.L. Bennell; W.F. Lems; M. van der Esch; T.P. Vliet Vlieland; R.W.J.G. Ostelo

QUESTION: In people with knee osteoarthritis, how much more effective is stratified exercise therapy that distinguishes three subgroups (high muscle strength subgroup, low muscle strength subgroup, obesity subgroup) in reducing knee pain and improving physical function than usual exercise therapy? DESIGN: …

2022AlgemeenArtikel

Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis: A randomized controlled trial protocol (OCTOPuS study).

J. Knoop; J Dekker; M van der Leeden; M. de Rooij; W.F. Peter; L. van Bodegom-Vos; J.M. van Dongen; N. Lopuhäa; K.L. Bennell; W.F. Lems; M. van der Esch; T.P. Vliet Vlieland; R.W.J.G. Ostelo

OBJECTIVES: Knee osteoarthritis (OA) is characterized by its heterogeneity, with large differences in clinical characteristics between patients. Therefore, a stratified approach to exercise therapy, whereby patients are allocated to homogeneous subgroups and receive a stratified, subgroup-specific intervention, …

2020AlgemeenArtikel

Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis

Knoop, Jesper; Dekker, Joost; van der Leeden, Marike; de Rooij, Mariëtte; Peter, Wilfred F. H.; van Bodegom-Vos, Leti; van Dongen, Johanna M; Lopuhäa, Nique; Bennell, Kim L.; Lems, Willem F.; van der Esch, Martin (Urban Vitality); Vliet Vlieland, Thea P.M.; Ostelo, Raymond W.J.G.

2020AlgemeenArtikel

The PRECIS-2 tool has good interrater reliability and modest discriminant validity

Loudon, Kirsty; Zwarenstein, Merrick; Sullivan, Frank; Donnan, Peter; Gágyor, Ildikó; Hobbelen, Hans (Ageing And Allied Health Care); Althabe, Fernando; Krishnan, Jerry A; Treweek, Shaun

OBJECTIVE: PRECIS - 2 is a tool that could improve design insight for trialists. Our aim was to validate the PRECIS - 2 tool, unlike its predecessor, testing the discriminant validity and inter-rater reliability. STUDY DESIGN AND SETTING: Over 80 international trialists, methodologists, clinicians and …

2017-06-08Gezondheid; …Artikel

HELP! Problems in executing a pragmatic, randomized, stepped wedge trial on the Hospital Elder Life Program to prevent delirium in older patients

Noor Heim; Henk F. van Stel; Roelof Ettema (Lid Lectoraat); Roos C. van der Mast; Sharon K. Inouye; Marieke Schuurmans (Lector)

Background: A pragmatic, stepped wedge trial design can be an appealing design to evaluate complex interventions in real-life settings. However, there are certain pitfalls that need to be considered. This paper reports on the experiences and lessons learned from the conduct of a cluster randomized, …

2017GezondheidArtikel

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Stratified exercise therapy does not improve outcomes compared with usual exercise therapy in people with knee osteoarthritis (OCTOPuS study): a cluster randomised trial.

Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis: A randomized controlled trial protocol (OCTOPuS study).

Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis

The PRECIS-2 tool has good interrater reliability and modest discriminant validity

HELP! Problems in executing a pragmatic, randomized, stepped wedge trial on the Hospital Elder Life Program to prevent delirium in older patients

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