Objective Assess improvable care factors in late preterm mortality, defined as death of a child during labour or in the first 28 days thereafter between 32 + 0 and 36 + 6 weeks gestation, in the Netherlands. Design Perinatal audit has been coordinated and supported at the national level, with selection …

Summary: Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate these pathway predictions. The Xpaths algorithms are applied …

Background: Roughly 200 million women become pregnant every year - most of them living in developing countries in Asia and Africa - many of these women suffer from ongoing nutritional deficiencies, contributing to the estimate of half a million maternal deaths a year. Educational programs teaching on …

Background: Having children or being childless is associated with differences in women's psychological wellbeing during the reproductive age period. Methods: An individually matched case-control cohort study, measuring psychological wellbeing with the 5-item Mental Health Inventory (MHI-5) was conducted. …

Adolescents' access to contraception and other sexual and reproductive health (SRH) services has been described in previous studies as a problem to many communities in Africa. The Department of Health and HelpHer.org provides sexual and reproductive health services to adolescents in Esidadeni through …

Implementation of reliable methodologies allowing Reduction, Refinement, and Replacement (3Rs) of animal testing is a process that takes several decades and is still not complete. Reliable methods are essential for regulatory hazard assessment of chemicals where differences in test protocol can influence …

Soybean and fishmeal are obtained in large quantities to produce animal feed. This puts an immense stress on today’s environment. Insect larvae are seen as a possible replacement of soybean and fishmeal but there is still a large knowledge gap preventing large scale production. Many species of insect …

Background: Marfan syndrome (MFS) is a heritable connective tissue disease caused by a defect in FBN1. The diagnosis is based on the revised Ghent criteria. The main features involve the cardiovascular, musculoskeletal, ophthalmic, pulmonary systems and facial features. Although the clinical manifestations …

Background: Urban slums are characterised by unique challenging living conditions, which increase their inhabitants’ vulnerability to specific health conditions. The identification and prioritization of the key health issues occurring in these settings is essential for the development of programmes that …

Higher education is tasked with preparing students for a culturally diverse and globalizing world. Additionally, western nations have an increasingly diverse student population and know the success of their students will depend in part on being able to navigate diversity. There is therefore good reason …