Objective Assess improvable care factors in late preterm mortality, defined as death of a child during labour or in the first 28 days thereafter between 32 + 0 and 36 + 6 weeks gestation, in the Netherlands. Design Perinatal audit has been coordinated and supported at the national level, with selection …

Summary: Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate these pathway predictions. The Xpaths algorithms are applied …

Background: Roughly 200 million women become pregnant every year - most of them living in developing countries in Asia and Africa - many of these women suffer from ongoing nutritional deficiencies, contributing to the estimate of half a million maternal deaths a year. Educational programs teaching on …

Parasitoids lay their eggs in or on a host, usually another insect. During foraging, parasitoids can encounter insects that differ in terms of host suitability and quality. At one extreme end of this spectrum are non-hosts that are unsuitable for offspring development.Non-hosts are generally ignored …

Communal breeding, wherein multiple conspecifics live and reproduce together, may generate short-term benefits in terms of defence and reproduction. However, its carry-over effects remain unclear. We experimentally tested the effects of communal breeding on parental care and reproduction in burying beetles …

Even in well-studied organisms, it is often challenging to uncover the social and environmental determinants of fitness. Typically, fitness is determined by a variety of factors that act in concert, thus forming complex networks of causal relationships. Moreover, even strong correlations between social …

Background: Having children or being childless is associated with differences in women's psychological wellbeing during the reproductive age period. Methods: An individually matched case-control cohort study, measuring psychological wellbeing with the 5-item Mental Health Inventory (MHI-5) was conducted. …

Adolescents' access to contraception and other sexual and reproductive health (SRH) services has been described in previous studies as a problem to many communities in Africa. The Department of Health and HelpHer.org provides sexual and reproductive health services to adolescents in Esidadeni through …

Animals can alter their foraging behavior through associative learning, where an encounter with an essential resource (e.g., food or a reproductive opportunity) is associated with nearby environmental cues (e.g., volatiles). This can subsequently improve the animal’s foraging efficiency. However, when …

Implementation of reliable methodologies allowing Reduction, Refinement, and Replacement (3Rs) of animal testing is a process that takes several decades and is still not complete. Reliable methods are essential for regulatory hazard assessment of chemicals where differences in test protocol can influence …