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Cancer cachexia: an overview of diagnostic criteria and therapeutic approaches for the accredited practicing dietitian

Barbara van der Meij; L Teleni; AL McCarthy; EA Isenring

Background: Cancer cachexia (CC) is a multifactorial syndrome characterised by ongoing skeletal muscle loss that leads to progressive functional impairment driven by reduced food intake and abnormal metabolism. Despite the traditional use of non-volitional weight loss as the primary marker of CC, there …

2021AlgemeenArtikel

Low muscle mass is associated with early termination of chemotherapy related to toxicity in patients with head and neck cancer

Sealy, Martine J. (Healthy Ageing, Allied Health Care And Nursing); Dechaphunkul, Tanadech; van der Schans, Cees P.; Krijnen, Wim P (Statistical Techniques For Applied Research); Roodenburg, Jan L. N.; Walker, John; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Baracos, Vickie E.

BACKGROUND & AIMS: We studied whether low pre-treatment muscle mass, measured with CT at thoracic (T4) or lumbar level (L3) associates with early termination of chemotherapy related to toxicity in head and neck cancer (HNC) patients. METHODS: This was a retrospective chart and image review. Adult HNC …

2020-02Gezondheid; …Artikel

Thirteen weeks of supplementation of vitamin D and leucine-enriched whey protein nutritional supplement attenuates chronic low-grade inflammation in sarcopenic older adults: the PROVIDE study

Liberman, Keliane; Njemini, Rose; Luiking, Yvette; Forti, Louis N.; Verlaan, Sjors; Bauer, Jürgen M.; Memelink, Robert (Faculteit Bewegen, Sport En Voeding); Brandt, Kirsten; Donini, Lorenzo; Maggio, Marcello; Mets, Tony; Weijers, Sander L.J.; Sieber, Cornel; Cederholm, Tommy; Bautmans, Ivan

Background: A chronic low-grade infammatory profle (CLIP) is associated with sarcopenia in older adults. Protein and Vitamin (Vit)D have immune-modulatory potential, but evidence for efects of nutritional supplementation on CLIP is limited. Aim To investigate whether 13 weeks of nutritional supplementation …

2019-06AlgemeenArtikel

Sarcopenia, a strong determinant for prolonged feeding tube dependency after chemoradiotherapy for head and neck cancer

Karsten, Rebecca T.; Al-Mamgani, Abrahim; Bril, Sandra I.; Tjon-A-Joe, Sheena; van der Molen, Lisette; de Boer, Jan P.; Hilgers, Frans J. M.; Smeele, Ludi E.; van den Brekel, Michiel W. M.; Stuiver, Martijn M.

BACKGROUND: Sarcopenia might be a relevant lead for optimization of the condition of patients with head and neck cancer (HNC) before chemoradiotherapy (CRT) to prevent long-term functional swallowing impairment, such as feeding tube dependency. METHODS: Regression analyses were performed to assess the …

2019AlgemeenArtikel

Association between computed tomography assessment of skeletal muscle index and muscle attenuation and chemotherapy intolerance in patients with head and neck cancer: preliminary results

Sealy, Martine (Healthy Ageing, Allied Health Care And Nursing); van der Schans, Cees; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Krijnen, Wim (Statistical Techniques For Applied Research); Roodenburg, Jan; Baracos, Vickie

2017Gezondheid; …Conferentiebijdrage

Skeletal muscle quality as assessed by CT-derived skeletal muscle density is associated with 6-month mortality in mechanically ventilated critically ill patients

Looijaard, Wilhelmus G.P.M.; Dekker, Ingeborg M.; Stapel, Sandra N.; Girbes, Armand R.J.; Twisk, Jos W.R.; Oudemans-van Straaten, Heleen M.; Weijs, Peter J.M. (Lectoraat Voeding En Beweging)

BACKGROUND: Muscle quantity at intensive care unit (ICU) admission has been independently associated with mortality. In addition to quantity, muscle quality may be important for survival. Muscle quality is influenced by fatty infiltration or myosteatosis, which can be assessed on computed tomography …

2016AlgemeenArtikel

Evaluation of bioelectrical impedance analysis in critically Ill patients

Kuchnia, Adam; Earthman, Carrie; Teigen, Levi; Cole, Abigail; Mourtzakis, Marina; Paris, Michael; Looijaard, Willem; Weijs, Peter (Lectoraat Voeding En Beweging); Oudemans-van Straaten, Heleen; Beilman, Gregory; Day, Andrew; Leung, Roger; Compher, Charlene; Dhaliwal, Rupinder; Peterson, Sarah; Roosevelt, Hannah; Heyland, Daren K

BACKGROUND: In critically ill patients, muscle loss is associated with adverse outcomes. Raw bioelectrical impedance analysis (BIA) parameters (eg, phase angle [PA] and impedance ratio [IR]) have received attention as potential markers of muscularity, nutrition status, and clinical outcomes. Our objective …

2016AlgemeenArtikel

Low skeletal muscle area is a risk factor formortality in mechanically ventilated critically illpatients

Weijs, Peter JM (Lectoraat Voeding En Beweging); Looijaard, Wilhelmus GPM; Dekker, Ingeborg M; Stapel, Sandra N; Girbes, Armand RJ; Oudemans-van Straaten, Heleen M; Beishuizen, Albertus

Abstract: INTRODUCTION: Higher body mass index (BMI) is associated with lower mortality in mechanically ventilated critically ill patients. However, it is yet unclear which body component is responsible for this relationship.

2014-01-13AlgemeenArtikel

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