This study explores the intent of designers involved in design for sustainability and how responsible innovation can be collectively implemented. To do so, a case study using situational analysis was conducted with graduates of the Fabricademy program: a 6-month program on textiles and new technologies …

Insulin sensitivity and metabolic flexibility decrease in response to bed rest, but the temporal and causal adaptations in human skeletal muscle metabolism are not fully defined. Here, we use an integrative approach to assess human skeletal muscle metabolism during bed rest and provide a multi-system …

This dissertation explores the transition of businesses towards regenerative practices that contribute simultaneously to social, ecological, and economic value. It addresses the challenge of moving from degenerative business models to those that actively rejuvenate and enhance systems. Through a hybrid …

In solving systemic design challenges designers co-create with professionals from various fields. In the context of innovation in healthcare practices, this study investigates design abilities that healthcare professionals develop by participating in co-design projects. We conducted a mixed-methods research …

Transitions can be facilitated through collective networked action, moving from coordinated learning towards more forceful interventions. This coordinated effort is challenging in more extended learning and innovation networks. Creating and maintaining an overview of activities within such a network …

In recent years, Dutch authorities have attempted to shift from formal to informal care responsibilities to meet an increasing demand for care. There is a growing expectation that social and healthcare professionals will actively involve, support, and collaborate with partners, family members, and others …

This study explores the application of systemic design approaches used in a complex commercial context to create positive and sustainable change. The case study was a business case on sustainable parenthood, in which the company tried to balance its ambitions for environmental sustainability with the …

Background and aims: Observational data indicate that diets rich in fruits and vegetables have a positive effect on inflammatory status, improve metabolic resilience and may protect against the development of non-communicable diseases. Nevertheless, experimental evidence demonstrating a causal relationship …

Implementing circular urban supply chains is a major economic transformation that can only work if significant coordination problems between the actors involved are solved.  This requires, on the one hand, the implementation of efficient urban collection technologies, where process industries collaborate …

We developed and piloted a course, called Changemakers, that supported interdisciplinary student-led action groups to identify social and environmental sustainability challenges and influence systemic change. By exposing students to dynamic and complex issues from multiple stakeholder perspectives, Changemakers …