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Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats

AH Stokes; C Planty; J Pion; P Ancian; A Rogue; C Bansard; J Silvano; D Papineau; N Ben Abdeljelil; G Maruggi; HF Song; C Spickler; K Blouin; G Dubois; LA Rodriguez; J Baumeister; AM Steff; E Destexhe

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections (LRTI) in infants, and toddlers and vaccines are not yet available. A pediatric RSV vaccine (ChAd155-RSV) is being developed to protect infants against RSV disease. The ChAd155-RSV vaccine consists of a recombinant …

2022AlgemeenArtikel

Implementing a Personalized Physical Therapy Approach (Coach2Move) Is Effective in Increasing Physical Activity and Improving Functional Mobility in Older Adults: A Cluster-Randomized, Stepped Wedge Trial.

W. Heij; L. Sweerts; Bart Staal; S. Teerenstra; E. Adang; P.J. van der Wees; M.W.G. Nijhuis -van der Sanden; T.J. Hoogeboom

OBJECTIVE: The purpose of this study was to assess whether the superior cost-effectiveness of a personalized physical therapy approach (Coach2Move)-which was demonstrated in a previous trial when compared to usual care physical therapy (UCP)-can be replicated in daily clinical practice. METHODS: A multicenter …

2022AlgemeenArtikel

The Cardiac Care Bridge transitional care program for the management of older high-risk cardiac patients

Verweij, Lotte; Petri, Adrianne C. M.; MacNeil-Vroomen, Janet L.; Jepma, Patricia; Latour, Corine H. M. (Lectoraat Geïntegreerde Complexe Zorg); Peters, Ron J. G.; Scholte op Reimer, Wilma J. M.; Buurman, Bianca M.; Bosmans, Judith E.

Objective To evaluate the cost-effectiveness of the Cardiac Care Bridge (CCB) nurse-led transitional care program in older (≥70 years) cardiac patients compared to usual care. Methods The intervention group (n = 153) received the CCB program consisting of case management, disease management and home-based …

2022AlgemeenArtikel

Expanding the environmental scope

van de Weijer, Margot P.; Baselmans, Bart M. L. (Faculteit Techniek (Ft)); Hottenga, Jouke-Jan; Dolan, Conor V.; Willemsen, Gonneke; Bartels, Meike

Background Identifying modifiable factors associated with well-being is of increased interest for public policy guidance. Developments in record linkage make it possible to identify what contributes to well-being from a myriad of factors. To this end, we link two large-scale data resources; the Geoscience …

2022AlgemeenArtikel

Assessing Changes in Fear of Movement in Patients attending Cardiac Rehabilitation

ter Hoeve, Nienke; Keessen, Paul (Lectoraat Oefentherapie); den Uijl, Iris; Visser, Bart (Lectoraat Oefentherapie); Kraaijenhagen, Roderik A.; Sunamura, Madoka; Scholte op Reimer, Wilma J. M.; Latour, Corine H. M. (Lectoraat Geïntegreerde Complexe Zorg); Jørstad, Harald T.; van den Berg-Emons, Hendrika J. G.

Objectives: The primary objective was to determine the responsiveness of the Dutch version of the 13-item Tampa Scale for Kinesiophobia for cardiac patients (TSK-NL Heart). The secondary objective was to assess changes in kinesiophobia during cardiac rehabilitation. Methods: Kinesiophobia was measured …

2022AlgemeenArtikel

On the Road Together: Issues Observed in the Process of a Research Duo Working Together in a Long-Term and Intense Collaboration in an Inclusive Research Project

Sofie Sergeant (Onderzoeker); Henriëtte Sandvoort (Onderzoeker); Geert Van Hove (Onderzoeker); Petri Embregts (Onderzoeker); Kim van den Bogaard (Onderzoeker); Elsbeth Taminiau (Onderzoeker); Alice Schippers (Onderzoeker)

Inclusive research practices can lead to progress towards an inclusive society. With this study, we aimed to gain insight into dilemmas and catalysing processes within the long-term collaboration of an inclusive research duo: one non-academic researcher who lives with the label of intellectual disabilities …

2022Mens & MaatschappijArtikel

The personal dimension of allied health professional identity

Eline E.W. Belgraver (Onderzoeker); Remco Coppoolse (Onderzoeker); Lia van Doorn (Lector); Cok Bakker (Lector)

Introduction: With a shift in healthcare from diagnosis-centered to human- and interprofessional-centered work, allied health professionals (AHPs) may encounter dilemmas in daily work because of discrepancies between values of learned professional protocols and their personal values, the latter being …

2022Filosofie & Religie; …Artikel

Inpatient physical activity across a large university city hospital: a behavioral mapping study

Karin Valkenet (Onderzoeker); Prue McRae (Onderzoeker); Elja Reijneveld (Onderzoeker); Mariëlle Jans (Onderzoeker); Petra Bor (Onderzoeker); Lotte van Delft (Onderzoeker); Daniel L. Young (Onderzoeker); Cindy Veenhof (Lector)

Background: Physical inactivity is common during hospitalization. Physical activity has been described in different inpatient populations but never across a hospital. Purpose: To describe inpatient movement behavior and associated factors throughout a single university hospital. Methods: A prospective …

2022GezondheidArtikel

A systematic approach to quantify the influence of indoor environmental parameters on students' perceptions, responses, and short-term academic performance

Henk W. Brink (Onderzoeker); Marcel G.L.C. Loomans (Onderzoeker); Mark P. Mobach (Onderzoeker); Helianthe S.M. Kort (Lector)

Several studies found that classrooms' indoor environmental quality (IEQ) can positively influence in-class activities. Understanding and quantifying the combined effect of four indoor environmental parameters, namely indoor air quality and thermal, acoustic, and lighting conditions on people is essential …

2022GezondheidArtikel

Digital health interventions to improve eating behaviour of people with a lower socioeconomic position: a scoping review of behaviour change techniques

Amber Ronteltap (Onderzoeker); Andrea J. Bukman (Onderzoeker); Gera E. Nagelhout (Onderzoeker); Roel C.J. Hermans (Onderzoeker); Karen Hosper (Onderzoeker); Annemien Haveman-Nies (Onderzoeker); Remko Lupker (Onderzoeker); Catherine A.W. Bolman (Onderzoeker)

Specific approaches are needed to reach and support people with a lower socioeconomic position (SEP) to achieve healthier eating behaviours. There is a growing body of evidence suggesting that digital health tools exhibit potential to address these needs because of its specific features that enable application …

2022GezondheidArtikel

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