BACKGROUND The mechanical power of ventilation (MP) has an association with outcome in invasively ventilated patients with the acute respiratory distress syndrome (ARDS). Whether a similar association exists in invasively ventilated patients without ARDS is less certain. OBJECTIVE To investigate the …

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

Sports are activities enjoyed by many across the globe, regardless of age. The existence and promotion of youth sports has often been based on various assumptions about its value and role in society. Sports participation is assumed to be fun and good and is assumed to contribute to the development of …

To successfully develop a system, a solid understanding of its architecture by stakeholders involved in the development of the system is key. This process is supported by System Architects, who have a profession that is often regarded as experience based. However, we argue that it is important to familiarize …

Increasingly, Design Thinking's influence reaches beyond the confines of traditional design disciplines and expands its role in connecting domains and integrating resources. This study focused on the changing role of design researchers involved in interdisciplinary research projects, following a Research-through-Design …

Psychologische instrumenten worden regelmatig gebruikt in de rechtbank om beeldvorming en besluitvorming te ondersteunen. Veel van deze instrumenten zijn echter oorspronkelijk niet ontwikkeld voor gebruik binnen deze context, wat vragen oproept over de validiteit en betrouwbaarheid van de uitkomsten. …

With the increasing presence of new media, life in classrooms all around the world has drastically changed. The critical and conscious use of media messages provided by technological devices has developed into a crucial 21st century skill. Lin et al. (2013) have laid ground for a useful and proven theoretical …

Background: Adverse outcome pathway (AOP) networks are versatile tools in toxicology and risk assessment that capture and visualize mechanisms driving toxicity originating from various data sources. They share a common structure consisting of a set of molecular initiating events and key events, connected …

Design education has a nuanced relationship with examples. Although they are considered useful teaching tools, their use is often restricted to illustrating the design theories and principles around which the curriculum is structured. In contrast, professional designers view examples as autonomous entities …