Background: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients. Methods: Baseline data from the …

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

Decentralized smart gas (energy) grid. Presentation given on the Energy Delta Convention PhD. Master Class 2012.

This final project has been assigned by ProDemos Huis voor Democratie en Rechtsstaat (House for Democracy and Rule of Law). This final project is a graduation paper for the bachelor degree European Studies from The Hague University of Applied Sciences. This benchmark research paper compares ProDemos …

Chapter 2 in Impacts of Emerging Economies and Firms on International Business. One of the most remarkable phenomena of recent times is that a large number of firms from emerging economies have come to define and dominate new markets and enter the class of global innovation leaders. Firms that once specialized …

Dit artikel doet verslag van een onderzoek naar studieprestaties bij het vak geschiedenis als gevolg van het gebruik van een interactief softwareprogramma dat is ontworpen om de leerlingen te laten leren door middel van digitale multimedia. In dit onderzoek wilden Kingsley en Boone meten of het gebruik …

This paper explores how residents of Helmond Brandevoort, a neotraditional neighbourhood in the Netherlands, socially construct a 'classed' place identity and what role the historicised architecture plays within that process. Given that place identity is constructed through social and cultural practices, …

Achtergrond: Het doel van deze studie is het evalueren van de aspecten van interbeoordelaarsbetrouwbaarheid van het PRPP-systeem (Perceive, Recall, Plan en Perform) van Taakanalyse voor het beoordelen van het dagelijks functioneren van thuiswonende patiënten met dementie. Methode: Video-opnames van 30 …

The focus of my research is how Bartholomeus Guesthouse (BG), founded in 1407 by Willem van Abcoude, has organized care over more than 600 years for the elderly and elderly sick people in the Centre of Utrecht. After the reorganization of 1817 -by Royal Law- the 7 (9) Guesthouses were merged to one …

Background: G-protein coupled receptors (GPCRs) are involved in many different physiological processes and their function can be modulated by small molecules which bind in the transmembrane (TM) domain. Because of their structural and sequence conservation, the TM domains are often used in bioinformatics …