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The Impact of Non-Pharmacological Interventions on Delirium in Neurological Intensive Care Unit Patients: A Single-Center Interrupted Time Series Trial

Paul Rood; Dharmanand Ramnarain

Abstract: Background: Delirium is a pathobiological brain process that is frequently observed in Intensive Care Unit (ICU) patients, and is associated with longer hospitalization as well as long-term cognitive impairment. In neurological ICU patients, delirium may be more treatment-resistant due to the …

2023-09GezondheidArtikel

Support for relatives in the intensive care unit: lessons from a cross-sectional multicentre cohort study during the COVID-19 pandemic

Sophie C. Renckens; H. Roeline Pasman (Phd); Hanna T. Klop; Chantal du Perron; Lia van Zuylen; MAH Steegers; Birkitt L. ten Tusscher; Floor C.H. Abbink; Wouter de Ruijter; Lilian Vloet (Lector); Stephanie C.E. Koster; Bregje D. Onwuteaka-Philipsen

Support for relatives is highly important in the intensive care unit (ICU). During the first COVID-19 wave support for relatives had to be changed considerably. The alternative support could have decreased the quality and sense of support. We aimed to evaluate how support for relatives in Dutch ICUs …

2023-07-18GezondheidArtikel

Towards precision medicine for septic patients

Bram Snoek (Student)

Sepsis is a life-threatening organ dysfunction caused by a dysregulated immune response to infection. It is the number one cause of death in the Intensive Care Unit (ICU), accounting for 6 million casualties every year. Unfortunately, all clinical trials in the last decade failed due to the highly complex …

2023-07-05Gezondheid; …Bachelor

Differences in Ventilation Management and Outcomes between the Two First Waves of the COVID-19 Pandemic—A Comparison between Two Nationwide Observational Studies in The Netherlands

The aim of this analysis was to compare ventilation management and outcomes in invasively ventilated patients with acute hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19) between the first and second wave in the Netherlands. This is a post hoc analysis of two nationwide observational …

2023-07-05AlgemeenArtikel

Patients with and Without COVID-19 in the Intensive Care Unit

Cijs, Bastiaan; Valkenet, Karin; Heijnen, Germijn; Visser-Meily, J M Anne; Van Der Schaaf, Marike (Lectoraat Revalidatie Bij Complexe Zorg)

Objective Many patients with coronavirus disease 2019 (COVID-19) infections were admitted to an intensive care unit (ICU). Physical impairments are common after ICU stays and are associated with clinical and patient characteristics. To date, it is unknown if physical functioning and health status are …

2023-07AlgemeenArtikel

The impact of high versus standard enteral protein provision on functional recovery following intensive care admission (PRECISE trial): study protocol for a randomized controlled, quadruple blinded, multicenter, parallel group trial in mechanically ventilated patients

Rob J.J. van Gassel (Onderzoeker); Julia L.M. Bels (Onderzoeker); Katrien Tartaglia (Onderzoeker); Bas C.T. Bussel (Onderzoeker); Sander M.J. van Kuijk (Onderzoeker); Adam M. Deane (Onderzoeker); Zudin Puthucheary (Onderzoeker); Peter Weijs (Onderzoeker); Lilian Vloet (Lector); Bert (A.) Beishuizen (Onderzoeker); Ashley de Bie Dekker (Onderzoeker); Vincent Fraipont (Onderzoeker); Stoffel Lamote (Onderzoeker); Didier Ledoux (Onderzoeker); Clarissa Scheeren (Onderzoeker); Elisabeth de Waele (Onderzoeker); Arthur R.H. van Zanten (Onderzoeker); Dieter Mesotten (Onderzoeker); Marcel C.G. van de Poll (Onderzoeker)

Critically ill patients are subject to severe skeletal muscle wasting during intensive care unit (ICU) stay, resulting in impaired short- and long-term functional outcomes and health-related quality of life. Increased protein provision may improve functional outcomes in ICU patients by attenuating skeletal …

2023-06-19GezondheidArtikel

Supportive care for relatives of patients dying in the intensive care setting: development of a toolbox (Project STRIC)

F.E. Witkamp; D. Enfield; R. Marijnissen-de Jong; D. Bolman; M. Bulut; J. Geraerdts; M. van de Haas; G. Konink; P. Spronk; C. den Uil; L. Vloet; S. Wagener; M. van Mol

The Intensive Care Unit (ICU) is characterised by high tech and absence of intimacy and often lacks a structured palliative care approach for bereavement support for relatives. We developed practical tools for ICU-nurses in the Netherlands to support relatives of dying patients in the ICU.

2023-05-16GezondheidAndersoortig materiaal

Relatives' experiences of the transition from intensive care to home for acutely admitted intensive care patients

Meiring-Noordstra, Aaltje; van der Meulen, Ingeborg C; Onrust, Marisa; Hafsteinsdóttir, Thóra B; Luttik, Marie Louise (Family Care)

BACKGROUND: Acute admission to an intensive care unit (ICU) can negatively affect quality of life for patients and their relatives. Relatives play an important caregiving role after the patient's admission. More knowledge and understanding of their needs are necessary as the patient transitions home. …

2023-05-08Mens & Maatschappij; …Artikel

Incidence of Air Leaks in Critically Ill Patients with Acute Hypoxemic Respiratory Failure Due to COVID-19

Goossen, Robin L.; Verboom, Mariëlle; Blacha, Mariëlle; Smesseim, Illaa; Beenen, Ludo F. M.; van Meenen, David M. P.; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

Subcutaneous emphysema, pneumothorax and pneumomediastinum are well-known complications of invasive ventilation in patients with acute hypoxemic respiratory failure. We determined the incidences of air leaks that were visible on available chest images in a cohort of critically ill patients with acute …

2023-03AlgemeenArtikel

Effect of mechanical power on mortality in invasively ventilated ICU patients without the acute respiratory distress syndrome

van Meenen, David M.P.; Algera, Anna Geke; Schuijt, Michiel T.U.; Simonis, Fabienne D.; van der Hoeven, Sophia M.; Neto, Ary Serpa; Abreu, Marcelo Gama de; Pelosi, Paolo; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

BACKGROUND The mechanical power of ventilation (MP) has an association with outcome in invasively ventilated patients with the acute respiratory distress syndrome (ARDS). Whether a similar association exists in invasively ventilated patients without ARDS is less certain. OBJECTIVE To investigate the …

2023-01AlgemeenArtikel

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