Bipolar disorder is a severe mental illness with serious consequences for daily living of patients and their caregivers. Care as usual primarily consists of pharmacotherapy and supportive treatment. However, a substantial number of patients show a suboptimal response to treatment and still suffer from …

What is already known about depression in dementia? Comorbid depression in people with dementia is associated with decreased quality of life (Shin et al., 2005), greater health care utilization (Kunik et al., 2003), higher mortality rates (Suh et al., 2005) and decreased caregiver’s wellbeing (Kerkstra …