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Cartilage tissue turnover increases with high- compared to low-intensity resistance training in patients with knee OA

Thudium, Christian S.; Engstrøm, Amalie; Bay-Jensen, Anne Christine; Frederiksen, Peder; Jansen, Nuria; De Zwart, Arjan; van der Leeden, Marike; Dekker, Joost; Lems, Willem; Roorda, Leo; van Spil, Willem Evert; Van der Esch, Martin (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

Objectives To investigate cartilage tissue turnover in response to a supervised 12-week exercise-related joint loading training program followed by a 6-month period of unsupervised training in patients with knee osteoarthritis (OA). To study the difference in cartilage tissue turnover between high- and …

2023AlgemeenArtikel

Patient Perspectives on Using a Smartphone App to Support Home-Based Exercise During Physical Therapy Treatment: Qualitative Study

Remco Arensman; Corelien Kloek; Martijn Pisters (Lector); Tjarco Koppenaal (Onderzoeker); Raymond Ostelo; Cindy Veenhof

Background: Home-based exercise is an important part of physical therapy treatment for patients with low back pain. However, treatment effectiveness depends heavily on patient adherence to home-based exercise recommendations. Smartphone apps designed to support home-based exercise have the potential …

2022-09-13GezondheidArtikel

Evaluation of allied healthcare in patients recovering from Covid-19

Objective: To report the study protocol and baseline characteristics of a prospective cohort study to evaluate longitudinal recovery trajectories of patients recovering from COVID-19 who have visited a primary care allied health professional. Design: Report of the protocol and baseline characteristics …

2022-08-26AlgemeenArtikel

Cost Effectiveness of Endovascular Revascularisation vs. Exercise Therapy for Intermittent Claudication Due to Iliac Artery Obstruction

van Reijen, Nick S.; van Dieren, Susan; Frans, Franceline A.; Reekers, Jim A.; Metz, Roderik; Buscher, Hessel C.J.L.; Koelemay, Mark J.W.

Objective To compare cost effectiveness of endovascular revascularisation (ER) and supervised exercise therapy (SET) as primary treatment for patients with intermittent claudication (IC) due to iliac artery obstruction. Methods Cost utility analysis from a restricted societal perspective and time horizon …

2022-03AlgemeenArtikel

Editor's Choice – Randomised Clinical Trial of Supervised Exercise Therapy vs. Endovascular Revascularisation for Intermittent Claudication Caused by Iliac Artery Obstruction

Objective : International guidelines recommend supervised exercise therapy (SET) as primary treatment for all patients with intermittent claudication (IC), yet primary endovascular revascularisation (ER) might be more effective in patients with iliac artery obstruction. Methods : This was a multicentre …

2022-03AlgemeenArtikel

The 3-Month Effectiveness of a Stratified Blended Physiotherapy Intervention in Patients With Nonspecific Low Back Pain: Cluster Randomized Controlled Trial

Tjarco Koppenaal (Onderzoeker); Martijn F. Pisters (Lector); Corelien JJ Kloek; Remco M. Arensman; Raymond WJG Ostelo; Cindy Veenhof

Background: Patient education, home-based exercise therapy, and advice on returning to normal activities are established physiotherapeutic treatment options for patients with nonspecific low back pain (LBP). However, the effectiveness of physiotherapy interventions on health-related outcomes largely …

2022-02-25GezondheidArtikel

The effect of interventions anticipated to improve plantar intrinsic foot muscle strength on fall-related dynamic function in adults: a systematic review

Lydia Willemse (Onderzoeker); Eveline Wouters (Lector); Henk Bronts (Onderzoeker); Martijn Pisters (Lector); Benedicte Vanwanseele (Onderzoeker)

Background The plantar intrinsic foot muscles (PIFMs) have a role in dynamic functions, such as balance and propulsion, which are vital to walking. These muscles atrophy in older adults and therefore this population, which is at high risk to falling, may benefit from strengthening these muscles in order …

2022-01-20GezondheidArtikel

No evidence for stratified exercise therapy being cost-effective compared to usual exercise therapy in patients with knee osteoarthritis: Economic evaluation alongside cluster randomized controlled trial.

J. Knoop; J. Esser; J Dekker; J.W. de Joode; R.W.J.G. Ostelo; J.M. van Dongen

BACKGROUND: A stratified approach to exercise therapy may yield superior clinical and economic outcomes, given the large heterogeneity of individuals with knee osteoarthritis (OA). OBJECTIVE: To evaluate the cost-effectiveness during a 12-month follow-up of a model of stratified exercise therapy compared …

2022AlgemeenArtikel

Stratified exercise therapy does not improve outcomes compared with usual exercise therapy in people with knee osteoarthritis (OCTOPuS study): a cluster randomised trial.

J. Knoop; J Dekker; J.M. van Dongen; M van der Leeden; M. de Rooij; W.F. Peter; W. de Joode; L. van Bodegom-Vos; N. Lopuhaä; K.L. Bennell; W.F. Lems; M. van der Esch; T.P. Vliet Vlieland; R.W.J.G. Ostelo

QUESTION: In people with knee osteoarthritis, how much more effective is stratified exercise therapy that distinguishes three subgroups (high muscle strength subgroup, low muscle strength subgroup, obesity subgroup) in reducing knee pain and improving physical function than usual exercise therapy? DESIGN: …

2022AlgemeenArtikel

Patients' and clinicians' experiences with stratified exercise therapy in knee osteoarthritis: a qualitative study.

J. Knoop; J.W. de Joode; H. Brandt; J Dekker; R.W.J.G. Ostelo

BACKGROUND: We have developed a model of stratified exercise therapy that distinguishes three knee osteoarthritis (OA) subgroups ('high muscle strength subgroup', 'low muscle strength subgroup', 'obesity subgroup'), which are provided subgroup-specific exercise therapy (supplemented by a dietary intervention …

2022AlgemeenArtikel

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