Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation and length of intensive care unit (ICU) stay. However, optimal …

INTRODUCTION: Mechanical Insufflation-Exsufflation (MI-E) is used as an airway clearance intervention in primary care (home ventilation), long-term care (prolonged rehabilitation after intensive care, neuromuscular diseases, and spinal cord injury), and increasingly in acute care in intensive care units …

Mechanical insufflation-exsufflation (MI-E) is traditionally used in the neuromuscular population. There is growing interest of MI-E use in invasively ventilated critically ill adults. We aimed to map current evidence on MI-E use in invasively ventilated critically ill adults. Two authors independently …

We weten steeds meer van onze bekende Nederlanders. Dit gaat van weten waar ze op vakantie zijn tot weten of ze ooit iemand hebben misbruikt. Waar het bij veel soorten media blijft bij het melden van de informatie, ondernemen radiostations actie. Blijf je een artiest draaien of haal je zijn muziek van …

This thesis is written on behalf of AFRIEK. AFRIEK is a fashion brand based in Rwanda which has the vision to show the power of cross-cultural collaboration based on equality. AFRIEK became much more of a research project than only a commercial brand: trying to be as sustainable as possible while keeping …

Dit rapport is geschreven naar aanleiding van het onderzoek naar de onveiligheidsgevoelens van de medewerkers van de Beschermd Wonen locaties in gebied B binnen Stichting Anton Constandse. De opdrachtgever gaf aan behoefte te hebben aan een onderzoek naar het onveiligheidsgevoel van de medewerkers tegenover …

BACKGROUND: The SpO2/FiO2 is a useful oxygenation parameter with prognostic capacity in patients with ARDS. We investigated the prognostic capacity of SpO2/FiO2 for mortality in patients with ARDS due to COVID-19. METHODS: This was a post-hoc analysis of a national multicenter cohort study in invasively …

We describe the incidence and practice of prone positioning and determined the association of use of prone positioning with outcomes in invasively ventilated patients with acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) in a national, multicenter observational study, …

PURPOSE: We investigated changes in ARDS severity and associations with outcome in COVID-19 ARDS patients. METHODS: We compared outcomes in patients with ARDS classified as 'mild', 'moderate' or 'severe' at calendar day 1, and after reclassification at calendar day 2. The primary endpoint was 28-day …

Airway care interventions may prevent accumulation of airway secretions and promote their evacuation, but evidence is scarce. Interventions include heated humidification, nebulization of mucolytics and/or bronchodilators, manual hyperinflation and use of mechanical insufflation-exsufflation (MI-E). Our …