Background: Society ages, and the incidence of physical limitations and frailty is increasing. For frail older adults, these limitations will lead to more assistance in daily living activities. A significant cause of physical limitation and frailty is sarcopenia, age-related loss of skeletal muscle mass, …

Rationale: Lean body mass, including muscle, is known to decrease with age, which may contribute to loss of physical function, an indicator of frailty. Moreover, low muscle thickness is considered an indicator of frailty in critically ill patients. However, little is known about the relationship between …

Rationale: Malnutrition is a common problem in patients with Chronic Obstructive Pulmonary Disease (COPD). Whereas estimation of fat-free muscle mass index (FFMi) with bio-electrical impedance is often used, less is known about muscle thickness measured with ultrasound (US) as a parameter for malnutrition. …

Background & aims: A low muscle mass before start of treatment and loss of muscle mass during chemotherapy is related to adverse outcomes in patients with cancer. In this randomized controlled trial, the effect of nutritional counseling on change in muscle mass and treatment outcome in patients with …

Rationale: Omega-3 polyunsaturated fatty acid (PUFA) supplementation is a promising therapy for cancer-relatedmalnutrition, which affects 20-70% of patients with cancer1,2. This systematic review aimed to examine the effects of oralomega-3 PUFA supplementation on muscle maintenance and quality of life …

Introduction A rapidly increasing patient group is older adults with obesity and type 2 diabetes. The risk of accelerated muscle loss is prominent in this patient group. This population could benefit from weight loss, at the cost of increased risk of muscle loss and sarcopenia. Previous studies showed …

Echografische spierdikte metingen van de m. rectus femoris kunnen gebruikt worden voor het kwantificeren van spiermassaverlies. Wanneer extensief spiermassaverlies optreedt, kan worden gesproken over sarcopenie. Deze metingen kunnen een goede aanvulling zijn op het diagnosticeren van sarcopenie bij ouderen. …

The world population is aging, which increases the prevalence of physical limitation and chronic diseases. A major cause of these physical limitation and chronic diseases is a low muscle mass (sarcopenia) and/or a high fat mass (obesity). Coexistence of sarcopenia and obesity, called sarcopenic obesity, …

Introduction: Neuromuscular diseases (NMD) are a heterogeneous group of acquired or inherited diseases affecting the peripheral nervous system and muscle mass. The consequences of NMD are loss of muscle mass, function, and posture. Loss of muscle mass causes weakness, a decrease in mobility and cardiac …

Objectives Chronic systemic low grade inflammation is associated with the age-related loss of muscle mass. Resistance exercise has been suggested to reduce or lower chronic systemic low grade inflammation. However, systemic chronic low-grade inflammation may adversely affect the adaptive response to …