BACKGROUND: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an unpredictable pharmacokinetic/pharmacodynamic profile. Conventional intermittent …

Saybolt is a petrochemical company that invest in different types of oils and fuels. Saybolt Vlaardingen has purchased a new Perkin Elmer Optima 8300 ICP-OES (Inductively coupled plasma optical-emission spectrometry) that must be validated. The ICP-OES is used to analyze metals in petroleum products. This …

Background & aims Plasma citrulline concentration is considered to be a marker for enterocyte metabolic mass and to reflect its reduction as may occur during intestinal dysfunction. Strenuous exercise can act as a stressor to induce small intestinal injury. Our previous studies suggest that this comprises …

For research to the composition of oxylipids in human plasma and tissue it was necessary to have an analytical method that can measure these lipids on very low concentrations. In this bachelor thesis the development of a LC-MS method will be discussed.

The performance of neural electrodes in physiological fluid, especially in chronic use, is critical for the success of functional electrical stimulation devices. Tips of the Utah electrode arrays (UEAs) were coated with sputtered iridium oxide film (SIROF) and activated iridium oxide film (AIROF) to …

Objectives Chronic systemic low grade inflammation is associated with the age-related loss of muscle mass. Resistance exercise has been suggested to reduce or lower chronic systemic low grade inflammation. However, systemic chronic low-grade inflammation may adversely affect the adaptive response to …

BACKGROUND & AIMS: Oral supplementation with vitamin D is recommended for older adults to maintain a sufficient 25-hydroxyvitamin D (25(OH)D) status throughout the year. While supplementation with vitamin D2 or D3 is most common, alternative treatment regimens exist which require further investigation …

Effects of plasma surface treatments on morphology and surface chemistry: Improving adhesion of powder coating systems to polypropylene substrates.

With sufficient electrical energy CO2 from the atmosphere, combined with water, can be converted to hydrocarbons. The first step in converting CO2 into a carbon based fuel is the dissociation of CO2 into CO and O. DIFFER explores the possibilities of this process by using a microwave plasma. This project …