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Predicting and implications of target volume changes of brain metastases during fractionated stereotactic radiosurgery

Eline Hessen (Onderzoeker); Jasper Nijkamp (Onderzoeker); Pim Damen (Onderzoeker); Michael Hauptmann (Onderzoeker); Bas Jasperse (Onderzoeker); Luc Dewit (Onderzoeker); Lotte Lutkenhaus (Onderzoeker); Emmy Lamers (Lid Lectoraat); Uulke van der Heide (Onderzoeker); Eugène Damen (Onderzoeker); Patrick Hanssens (Onderzoeker); Gerben Borst (Onderzoeker)

a b s t r a c t: Objective: To study the impact of target volume changes in brain metastases during fractionated stereotactic radiosurgery (fSRS) and identify patients that benefit from MRI guidance. Material and methods: For 15 patients (18 lesions) receiving fSRS only (fSRSonly) and 19 patients (20 …

2019GezondheidArtikel

Effectiviteit in stadiëring van prostaatcarcinomen: Ga68-PSMA vs. F18-Choline

Celine Dijkstra (Student); Desirée Uildriks (Student); Janine Baër (Begeleider); Ruurd Visser (Begeleider)

Voor de stadiëring van een prostaatcarcinoom wordt gebruik gemaakt van beeldvormend onderzoek, waaronder nucleair geneeskundig onderzoek als PET/CT of een whole body skeletscintigrafie. Doel van het onderzoek is het maken van een inschatting welke techniek (Ga68-PSMA PET/CT of F18-Choline PET/CT) effectiever …

2018-12-31GezondheidBachelor

Suitable sexual health care according to men with prostate cancer and their partners

Grondhuis Palacios, L.A. (Lorena) (Researcher); Krouwel, E.M. (Esmee) (Researcher); Oudsten, B.L. (Brenda) den (Researcher); Ouden, M.E.M. (Marjolein) den (Researcher); Kloens, G.J. (Gert Jan) (Researcher); Duijn, G. (Grethe) van (Researcher); Putter, H. (Hein) (Researcher); Pelger, R.C.M. (Rob) (Researcher); Elzevier, H.W. (Henk) (Researcher)

Purpose:To determine which health care provider and what timing is considered most suitable to discuss sexual and relationalchanges after prostate cancer treatment according to the point of view of men and their partners. Methods A cross-sectional survey was conducted among men diagnosed with prostate …

2018-06-01AlgemeenArtikel

Aanpassing van de standaard veldgrootte bij laterale liggende knie opnames

Lisanne Uffen (Student); Janniek Koning (Student); H. Erenstein (Begeleider)

In de praktijk komt het voor dat de standaard veldgrootte onnodig wordt vergroot, zonder dat MBB’ers zich hier bewust van zijn. Hierdoor ontvangt de patiënt onnodig meer dosis en wordt het ALARA-principe niet nageleefd. De veldgrootte wordt onnodig aangepast bij laterale knie opnames. Hierdoor ontstaat …

2018-05-31GezondheidBachelor

Durable clinical remission of a skull metastasis under intralesional Viscum album extract therapy

Paul G. Werthmann (Onderzoeker); Roman Huber (Onderzoeker); Gunver S. Kienle (Onderzoeker)

Background Skull metastases are rare, they can eventually cause pain, and can invade the brain. Viscum album extracts (VAEs) are used as an adjuvant treatment in cancer. Methods and Results A 68‐year‐old patient with rectal cancer presented with lung metastases, and metastases to multiple bone sites, …

2018GezondheidArtikel

How radiation influences atherosclerotic plaque development

Harmen Bijwaard (Lector)

Atherosclerosis is the development of lipid-laden plaques in arteries and is nowadays considered as an inflammatory disease. It has been shown that high doses of ionizing radiation, as used in radiotherapy, can increase the risk of development or progression of atherosclerosis. To elucidate the effects …

2017-08-21GezondheidArtikel

Multivariable normal tissue complication probability model-based treatment plan optimization for grade 2-4 dysphagia and tube feeding dependence in head and neck radiotherapy

Kierkels, Roel G J; Wopken, Kim; Visser, Ruurd; Korevaar, Erik W; van der Schaaf, Arjen; Bijl, Hendrik P; Langendijk, Johannes A

BACKGROUND AND PURPOSE: Radiotherapy of the head and neck is challenged by the relatively large number of organs-at-risk close to the tumor. Biologically-oriented objective functions (OF) could optimally distribute the dose among the organs-at-risk. We aimed to explore OFs based on multivariable normal …

2016-12AlgemeenArtikel

Reconstruction of high resolution MLC leaf positions using a low resolution detector for accurate 3D dose reconstruction in IMRT

Visser, R.; Godart, J.; Wauben, D.J.L.; Langendijk, J.A.; van 't Veld, A.A.; Korevaar, E.W.

In pre-treatment dose verification, low resolution detector systems are unable to identify shifts of individual leafs of high resolution multi leaf collimator (MLC) systems from detected changes in the dose deposition. The goal of this study was to introduce an alternative approach (the shutter technique) …

2016-11-07AlgemeenArtikel

Prediction model to predict critical weight loss in patients with head and neck cancer during (chemo)radiotherapy

Langius, Jacqueline A.E.; Twisk, Jos; Kampman, Martine; Doornaert, Patricia; Kramer, Mark H.H.; Weijs, Peter J.M. (Lectoraat Voeding En Beweging); Leemans, C. René

OBJECTIVES: Patients with head and neck cancer (HNC) frequently encounter weight loss with multiple negative outcomes as a consequence. Adequate treatment is best achieved by early identification of patients at risk for critical weight loss. The objective of this study was to detect predictive factors …

2016-01AlgemeenArtikel

Development of an iterative reconstruction method to overcome 2D detector low resolution limitations in MLC leaf position error detection for 3D dose verification in IMRT

Visser, Ruurd; J., Godart; Wauben, D.J.L.; Langendijk, J.; van 't Veld, A.A.; Korevaar, E.W.

The objective of this study was to introduce a new iterative method to reconstruct multi leaf collimator (MLC) positions based on low resolution ionization detector array measurements and to evaluate its error detection performance. The iterative reconstruction method consists of a fluence model, a detector …

2016AlgemeenArtikel

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