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Dose-response effects of supplementation with calcifediol on serum 25-hydroxyvitamin D status and its metabolites

Vaes, Anouk M.M.; Tieland, Michael (Lectoraat Voeding En Beweging); de Regt, Margot F.; Wittwer, Jonas; van Loon, Luc J.C.; de Groot, Lisette C.P.G.M.

BACKGROUND & AIMS: Oral supplementation with vitamin D is recommended for older adults to maintain a sufficient 25-hydroxyvitamin D (25(OH)D) status throughout the year. While supplementation with vitamin D2 or D3 is most common, alternative treatment regimens exist which require further investigation …

2018-06AlgemeenArtikel

Minerals and sarcopenia; the role of calcium, iron, magnesium, phosphorus, potassium, selenium, sodium, and zinc on muscle mass, muscle strength, and physical performance in older adults

van Dronkelaar, Carliene (Lectoraat Voeding En Beweging); van Velzen, Aafke; Abdelrazek, Maya; van der Steen, Anouk (Faculteit Bewegen, Sport En Voeding); Weijs, Peter J M (Lectoraat Voeding En Beweging); Tieland, Michael (Lectoraat Voeding En Beweging)

INTRODUCTION: Minerals may contribute to prevent and treat sarcopenia, the age-related loss of muscle mass, muscle strength, and physical performance. So far, there is no comprehensive review on the impact of minerals on sarcopenia outcomes. The aim of this systematic review is to evaluate the role of …

2018-01AlgemeenAndersoortig materiaal

An Even Distribution of Protein Intake Daily Promotes Protein Adequacy but Does Not Influence Nutritional Status in Institutionalized Elderly

Tieland, Michael (Lectoraat Voeding En Beweging); Beelen, Janne; Laan, Anna C M; Poon, Shirley; de Groot, Lisette C P G M; Seeman, Ego; Wang, Xiaofang; Iuliano, Sandra

OBJECTIVE: Although it has been established that sufficient protein is required to maintain good nutritional status and support healthy aging, it is not clear if the pattern of protein consumption may also influence nutritional status, especially in institutionalized elderly who are at risk of malnutrition. …

2018-01AlgemeenArtikel

SUN-P297 - Minerals and sarcopenia; the role of calcium, iron, magnesium, phosphorus, potassium, selenium, sodium, and zinc on muscle mass, muscle strength, and physical performance in older adults

van Dronkelaar, D.C. (Lectoraat Voeding En Beweging); van Velzen, Aafke; Abdelrazek, Maya; van der Steen, A. (Faculteit Bewegen, Sport En Voeding); Weijs, P.J.M. (Lectoraat Voeding En Beweging); Tieland, C.A.B. (Lectoraat Voeding En Beweging)

Rationale: Minerals may contribute to prevent and treat sarcopenia, the age-related loss of muscle mass, muscle strength, and physical performance. The aim of this systematic review is to evaluate the role of calcium, iron, magnesium, phosphorus, potassium, selenium, sodium, and zinc on muscle mass, …

2017-09AlgemeenArtikel

Seasonal variation in vitamin D status in elite athletes

Evelien Backx (Onderzoeker); Cindy van der Avoort; Michael Tieland; Kamiel Maase; Arie Kies; Luc van Loon; Lisette de Groot; Marco Mensink

Studies monitoring vitamin D status in athletes are seldom conducted for a period of 12 months or longer, thereby lacking insight into seasonal fluctuations. The objective of the cur-rent study was to identify seasonal changes in total 25-hydroxyvitamin D (25(OH)D) concen-tration throughout the year. …

2017Recreatie, Beweging & SportArtikel

Improved Efficacy of Oral Immunotherapy Using Non-Digestible Oligosaccharides in a Murine Cow's Milk Allergy Model

Marlotte M. Vonk (Onderzoeker); Mara A.P. Diks (Onderzoeker); Laura Wagenaar (Onderzoeker); J.J. Smit (Onderzoeker); Raymond Pieters (Lector); Johan Garssen (Onderzoeker); Betty C.A.M. van Esch (Onderzoeker); Léon M.J. Knippels (Onderzoeker)

From teh UU repository: "Background: Oral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, there are some concerns regarding its safety and long-term efficacy. The use of non-digestible oligosaccharides might improve OIT efficacy since they are known to …

2017GezondheidArtikel

Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

Christiane Hammerschmidt-Kamper (Onderzoeker); Daniel Biljes (Onderzoeker); Katja Merches (Onderzoeker); Irina Steiner (Onderzoeker); Daldrup Thomas (Onderzoeker); Marianne Bol-Schoenmakers (Onderzoeker); Raymond Pieters (Lector); Charlotte Esser (Onderzoeker)

From PLoS website: In general, dietary antigens are tolerated by the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) by the environmental …

2017GezondheidArtikel

The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow's milk- and peanut allergy models

Marlotte M. Vonk (Onderzoeker); Laura Wagenaar (Onderzoeker); Raymond Pieters (Lector); Léon M.J. Knippels (Onderzoeker); L.E.M. Willemsen (Onderzoeker); J.J. Smit (Onderzoeker); BCAM van Esch (Onderzoeker); J. Garssen (Onderzoeker)

From Pubmed: " BACKGROUND: Antigen-specific immunotherapy (AIT) is a promising therapeutic approach for both cow's milk allergy (CMA) and peanut allergy (PNA), but needs optimization in terms of efficacy and safety. AIM: Compare oral immunotherapy (OIT) and subcutaneous immunotherapy (SCIT) in …

2017GezondheidArtikel

Het opzetten van een ELISA om auto-antistoffen tegen Factor H te detecteren & De ontwikkeling van een stabiele ELISA standaard door middel van de chimerisatie van een anti-Factor H mAb

Bas van Aalst (Student)

Since Factor H is the main regulator of the complement system, any dysregulation may result in either uncontrolled complement activation or inhibition. Auto-antibodies against Factor H inhibit the protective function of Factor H on host cells, which are now sensitive for complement activation. It is …

2016-11-28Gezondheid; …Bachelor

De ontwikkeling van een multicomponent-analysemethode voor het bepalen van antidepressiva in bloedserum met LC-MS2

Martijn Böhm (Student)

Het laboratorium van de ziekenhuisapotheek van het OLVG bepaalt de concentratie van 13 antidepressiva in serum met behulp van de techniek LC-MS2. Alle antidepressiva worden nu met verschillende analysemethode geanalyseerd. Het laboratorium wil graag één uniforme multicomponent analysemethode voor het …

2016-01-26TechniekBachelor

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