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Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects

Sonja Beken; Peter T. Theunissen (Lid Lectoraat); Bruce K. Beyer

nd co-authors , William J. Breslin, Gregg D. Cappon, Connie L. Chen, Gary Chmielewski, Luc De Schaepdrijver, Brian Enright, Jennifer E. Foreman, Wafa Harrouk, Kok-Wah Hew, Alan M. Hoberman, Julia Y. Hui, Thomas B. Knudsen, Susan B. Laffan, Susan L. Makris, Matt Martin, Mary Ellen McNerney, Christine …

2016-10-19Gezondheid; …Artikel

Prediction of carcinogenic potential of chemicals using repeated-dose (13-week) toxicity data

Mirjam Luijten; Jan van Benthem; E.D. Kroese; Ruud A. Woutersen; Cyrille A.M. Krul (Lector); Ans E.M.F. Soffers; Jan Willem van der Laan

From the article: Abstract Sub-chronic toxicity studies of 163 non-genotoxic chemicals were evaluated in order to predict the tumour outcome of 24-month rat carcinogenicity studies obtained from the EFSA and ToxRef databases. Hundred eleven of the 148 chemicals that did not induce putative preneoplastic …

2016-09-08Gezondheid; …Artikel

Validation; truth or dare! [Abstract].

Marc Teunis (Lid Lectoraat); Cyrille Krul (Lector); Raymond Pieters (Lector)

n.a.

2015-10-16Natuur & LandbouwArtikel

Role of the immune system in DILI

Raymond Pieters (Lector)

n.a. doi:10.1016/j.toxlet.2015.08.109

2015-10-16Techniek; …Artikel

Validation of the innovative ToxTracker® genotoxicity reporter assay

Marc Teunis (Lid Lectoraat); Mieke Smits (Lid Lectoraat); H. Besselink; L.R.A. Jonker; G. Hendriks; E Adriaens

2015-09-29Gezondheid; …Recensie

Development of a self-management intervention for employees with complaints of the arm, neck and/or shoulder (CANS): a focus group study with experts.

Nathan Hutting; Josephine Engels; Bart Staal; Yvonne Heerkens; Ria Nijhuis-van der Sanden

BACKGROUND: Many people suffer from complaints of the arm, neck and/or shoulder (CANS). The complaints are persistent and there is a need for intervention programs for those with longstanding CANS. Studies suggest that a behavioural change is needed in employees with CANS. A self-management program with …

2015AlgemeenArtikel

Toxicity assessment of air-delivered particle-bound polybrominated diphenyl ethers

Luthe, G. (Gregor) (Lector)

Human exposure to polybrominated diphenyl ethers (PBDEs) can occur via ingestion of indoor dust, inhalation of PBDE-contaminated air and dust-bound PBDEs. However, few studies have examined the pulmonary toxicity of particle-bound PBDEs, mainly due to the lack of an appropriate particle-cell exposure …

2014-01-01AlgemeenArtikel

The association between prescription change frequency, chronic disease score and hospital admissions: a case control study

M.J. Schuurmans (Lector); A.C.G. Egberts; R. Stuffken; P.C. Souverein; Carolien Sino (Lid Lectoraat); Rob Heerdink

The aim of this study was to assess the association between prescription changes frequency (PCF) and hospital admissions and to compare the PCF to the Chronic Disease Score (CDS). The CDS measures comorbidity on the basis of the 1-year pharmacy dispensing data. In contrast, the PCF is based on prescriptionchanges …

2013-08-01GezondheidArtikel

Analyse van specifieke bewegingskenmerken bij personen met valrisico analyse van specifieke bewegingskenmerken bij personen met valrisico

Niek Theelen (Student); Ruud Berkers (Student); King Shing Yan (Student); Gus van Helvoirt (Student); Walter van der Weegen (Begeleider); Tom Melai (Begeleider)

Doel In opdracht van The Department of Human Movement Science, Nutrition and Toxicology Research Institute Maastricht, Universiteit Maastricht is getracht significante verschillen in bewegingskenmerken aan te tonen, bij ouderen met valrisico en zonder valrisico met behulp van een ETB accelerometer, tijdens …

2008GezondheidBachelor

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