BACKGROUND: Since the benefit-harm balance of adding inhaled corticosteroids to long-acting β2-agonists (LABA) and long-acting muscarinic antagonists (LAMA) for patients with chronic obstructive pulmonary disease is unclear, we evaluated this addition for a range of patient profiles. METHODS: Analyses …

We investigate the relationship between firm performance and patterns of exploration and exploitation dynamics under conditions of environmental turbulence. Adopting a contingency perspective, we develop arguments on how environmental turbulence moderates the effects of the simultaneous or sequential …

Evidence-based practice (EBP) is the integration of the current best evidence, with clinical expertise and patient values in the decision making about the care of individual patients. This concept has been widely adopted by the profession of physiotherapy. The application and practice of EBP by physiotherapists …

This work focuses on humidity effects of turbofan engines, in order to identify the magnitude of the error in operational conditions and the implications on maintenance decision support. More specifically, this paper employs a set of different methods, including semi-empirical corrections used in engine …

This study examined the association of sport participation with health outcomes and whether this relation differs between body mass index (BMI)-level subpopulations. Research outcomes for sport participation were compared with other types of leisure-time physical activity (PA). We used the Cox proportional …

This paper studies the factors that drive distribution structure design (DSD), which includes the spatial layout of distribution channels and location choice of logistics facilities. We build on a generic framework from existing literature, which we validate and elaborate using interviews among industry …

The carbon sink capacity of tropical forests is substantially affected by tree mortality. However, the main drivers of tropical tree death remain largely unknown. Here we present a pan-Amazonian assessment of how and why trees die, analysing over 120,000 trees representing > 3800 species from 189 long-term …

Participating in physical activity at a moderate-and-vigorous-intensity-level is recommended for teenagers to advance in health benefits. However, due to the fitness differences, the amount of physical activity to reach the recommended intensity varies among teenagers. Therefore, tailoring the physical …

Frailty is the most common manifestation of serious health issues in the world, and it is becoming more prevalent worldwide as the aging population grows. Changes that occur in an individual during the aging process have physical, psychological, social, and environmental aspects that make an individual …

The increasing demand on renewable energy in the past decade resulted in the development of more windmill parks in the north-sea. The north-sea is an ideal sea for the development of offshore structures such as windmill parks due to its morphological benefits of being a shallow sea with soft soils consist …