Since Factor H is the main regulator of the complement system, any dysregulation may result in either uncontrolled complement activation or inhibition. Auto-antibodies against Factor H inhibit the protective function of Factor H on host cells, which are now sensitive for complement activation. It is …

Disorders of Sex Development (DSD)-patiënten zijn patiënten met een congenitale conditie waarbij de chromosomale, gonadale of de anatomische geslachtsontwikkeling atypisch is. Bepaalde groepen patiënten gediagnostiseerd met DSD hebben een verhoogd risico op het ontwikkelen van een kwaadaardige kiemceltumor …

In a continuation of a prospective longitudinal cohort study in a healthy population on the course of skull shape from birth to 24 months, at 5 years of age, 248 children participated in a follow-up assessment using plagiocephalometry (ODDI-oblique diameter difference index, CPI-cranio proportional index). …

STUDY DESIGN A prospective cohort study within care as usual. OBJECTIVE 1. To explore the psychometric properties of a baseline disability questionnaire designed to collect patients expectation. 2. To analyse relationships between satisfaction with care and treatment success in patients with CLBP. 3. …

PURPOSE: To investigate the reliability and validity of the SQUASH physical activity (PA) questionnaire in a multi-ethnic population living in the Netherlands. METHODS: We included participants from the HELIUS study, a population-based cohort study. In this study we included Dutch (n = 114), Turkish …

In opdracht van het Studiesuccescentrum te Saxion is er onderzoek gedaan naar de voorspellende waarde van de vragenlijst Dimensie 0. Deze vragenlijst beoogt het keuzeproces en de motivatie van aspirant studenten te meten en maakt onderdeel uit van het intakeassessment van Saxion. Het intakeassessment …

Nontraumatic complaints of arm, neck, and shoulder (CANS) represent an important health issue, with a high prevalence in the general working age population and huge economic impact. Nevertheless, only few prospective cohort studies for the outcome of CANS are available.

Drop-out from the nursing profession is increasing, while at the same time the healthcare job market is rapidly expanding. Research on retaining nurses from the start of their career is scarce. The overall aim of the SPRiNG project is to develop a targeted program addressing the resilience of new graduate …

BACKGROUND: Many intensive care unit survivors (ICU) are confronted with undesirable and long-lasting impairments in physical, cognitive, and mental health, but not only patients are at risk of developing this post-intensive care syndrome (PICS). Family members can experience symptoms of depression, …