For hypertensive women in CHIPS (Control of Hypertension in Pregnancy Study), we assessed whether the maternal benefits of tight control could be achieved, while minimizing any potentially negative effect on fetal growth, by delaying initiation of antihypertensive therapy until later in pregnancy. For …

Background Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine skin tumor with frequent local recurrence, lymph node involvement, distant metastasis, and a high mortality rate. Viscum album extracts (VAE) are a widely used adjunct in cancer treatment and show cytotoxic and immune-modulating …

OBJECTIVE: The World Health Organization (WHO) recently proposed an Integrated Care for Older People approach to guide health systems and services in better supporting functional ability of older people. A knowledge gap remains in the key elements of integrated care approaches used in health and social …

This paper presents the results of the research project ‘Going Eco, Going Dutch’ (2015- 2017), which investigated the production, design and branding of fashion textiles made from locally produced hemp fibers in the Netherlands. For fashion labels and designers it is often difficult to scrutinize the …

Complex interventions are criticized for being a “black box”, which makes it difficult to determine why they succeed or fail. Recently, nine proactive primary-care programs aiming to prevent functional decline in older adults showed inconclusive effects. The aim of this study was to systematically unravel, …

In order to make exoskeletons more useful for a larger variety of users, especially within healthcare, it is of utmost importance to improve its wear ability. The scope of the XoSoft project is to develop a soft, wearable and comfortable soft exoskeleton. Here we describe the partial research on the …

Background Insufficient postmatch recovery in elite players may cause an increased risk of injuries, illnesses and non-functional over-reaching. Objective To evaluate postmatch recovery time courses of physical performance and biochemical markers in team ball sport players. Study design Systematic review. …

In one-dimensional disordered wires electronic states are localized at any energy. Correlations of the states at close positive energies and the AC conductivity \sigma(\omega) in the limit of small frequency are described by the Mott-Berezinskii theory. We revisit the instanton approach to the statistics …

This dissertation describes a research project about the communication between communication vulnerable people and health care professionals in long-term care settings. Communication vulnerable people experience functional communication difficulties in particular situations, due to medical conditions. …

BACKGROUND: To evaluate the effect of (new) treatments or analyse prevalence and risk factors of contractures, rating scales are used based on joint range of motion. However, cut-off points for levels of severity vary between scales, and it seems unclear how cut-off points relate to function. The purpose …