Background: G-protein coupled receptors (GPCRs) are involved in many different physiological processes and their function can be modulated by small molecules which bind in the transmembrane (TM) domain. Because of their structural and sequence conservation, the TM domains are often used in bioinformatics …

Background: Drug resistance is a major problem in ovarian cancer. Triggering apoptosis using death ligands such as tumour necrosis factor-related apoptosis inducing ligand (TRAIL) might overcome chemoresistance. Methods: We investigated whether acquired cisplatin resistance affects sensitivity to recombinant …

The differences between Chinese aid and traditional aid can be found in all aspects of the traditional and Chinese aid policies. Significant differences have been illustrated in its history, principles and in the impact on the recipient countries. The landmarks in the historical development of the Chinese …

Although sustainability is often discussed solely in ecological terms, it cannot be disconnected from the way humans behave in their social environment. This article presents a theoretical approach toward sustainability that takes a human behavior and knowledge view on sustainability as a starting point. …

In November 2006, SOMO published a report that criticised labour conditions in Nokia's factories in Asia. This report revealed conditions where workers work up to 72 hours a week with compulsory overtime, have insecure employment contracts and work in unsafe factories, where no or inadequate protection …

COS Zuid Holland Zuid's main mission is to broaden the basis for international cooperation. This means attracting new groups to get more involved in international cooperation. COS ZHZ already does very well in strengthening the existing basis for international cooperation, however reaching for new target …