BACKGROUND: The design and manufacturing of effective foot orthoses is a complex multidisciplinary problem involving biomedical and gait pattern aspects, technical material and geometric design elements as well as psychological and social contexts. This complexity contributes to the current trial-and-error …

Sickness absenteeism among flight crews is a pervasive problem disruptive to operations and costly for the employer. According to literature, exposure to certain schedule attributes has been associated with adverse health issues. However, the relationship between schedule characteristics and sickness …

An important step towards improving performance while reducing weight and maintenance needs is the integration of composite materials into mechanical and aerospace engineering. This subject explores the many aspects of composite application, from basic material characterization to state-of-the-art advances …

Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

This paper introduces a novel distributed algorithm designed to optimize the deployment of access points within Mobile Ad Hoc Networks (MANETs) for better service quality in infrastructure less environments. The algorithm operates based on local, independent execution by each network node, thus ensuring …

In this TechForFuture project ‘Polymer Mixing in a Single Screw Extruder’ a method to optimize mixing elements is developed based on numerical simulations (Computational Fluid Dynamics, CFD). A numerical procedure is developed to calculate the flow field in the extruder. By tracing particles in this …

In this TechForFuture project ‘Polymer Mixing in a Single Screw Extruder’ a method to optimize mixing elements is developed based on numerical simulations (Computational Fluid Dynamics, CFD). A numerical procedure is developed to calculate the flow field in the extruder. By tracing particles in this …

Despite tremendous efforts, the exact structure of SARS-CoV-2 and related betacoronaviruses remains elusive. SARS-CoV-2 envelope is a key structural component of the virion that encapsulates viral RNA. It is composed of three structural proteins, spike, membrane (M), and envelope, which interact with …

The number of Electric Vehicles (EVs) is expected to increase exponentially in the coming years. The growing presence of charging points generates a multitude of interactions between EV users, particularly in metropolitan areas where a charging infrastructure is largely part of the public domain. There …

Dynamic inflow effects occur due to the rapid change of the rotor loading under conditions such as fast pitch steps. The paper presents a setup suitable for the investigation of those effects for non-axisymmetric rotor conditions, namely individual pitch steps. Furthermore, insights into the relevant …