French/English abstract: Les systèmes d’aide à la prise de décision jouent un rôle important dans la pratique juridique aux Pays-Bas. Divers organismes gouvernementaux utilisent de tels systèmes automatisés pour la prise de décisions juridiques (de masse). Les départements juridiques, les cabinets d’avocats, …

Although essential for providing optimal adolescent patient support, knowledge of the impact of Marfan syndrome in adolescence is limited. To explore adolescents’ perceived impact of Marfan syndrome on (physical) functioning (activities, participation), disability (limitations, restrictions), contextual …

BACKGROUND: Scar contracture is a well-known sequela of burns that is specifically relevant as it may limit function. Reports regarding the course of scar contractures, however, are scarce and, moreover, not focussed on function. This study describes the course of prevalence of scar contractures that …

Students growing up with a family member with a chronic illness often delay or drop out of school when the combination of family care and their educational programme is too demanding. This study aims to describe the themes experienced by students growing up in this situation. A qualitative focus group …

BACKGROUND: Students living with a chronically ill family member may experience significant pressure, stress, and depression due to their caregiving situation. This may also lead to them delaying or dropping out of school when the combination of being a caregiver and their education program are too demanding. …

BACKGROUND: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an unpredictable pharmacokinetic/pharmacodynamic profile. Conventional intermittent …

: To have sustainable societies, we need to accelerate the energy transition towards clean energy solutions, however, awareness and understanding of the process is still limited, especially among young people. In addition, the topic has mainly been approached from an engineering angle, ignoring the social …

The capacity to utilize ingested protein for optimal support of protein synthesis and lean body mass is described within the paradigm of anabolic competence. Protein synthesis can be stimulated by physical exercise, however, it is not known if physical exercise affects post-exercise protein oxidation. …

Achtergrond Informele ouderlijke steun wordt gezien als kansrijke interventie voor het reduceren van opvoedstress. Er is echter weinig bekend over hoe relaties tussen ouders met en zonder opvoedstress zich ontwikkelen in opvoedingssituaties waarbij de ene partij ondersteuning geeft en de andere partij …

Background: The aim of this study is to investigate whether age of infant motor milestone achievement is related to levels of physical activity (PA), weight status and blood pressure at age 4–7years of age. Methods: In the Dutch GECKO (Groningen Expert Center of Kids with Obesity) Drenthe cohort, the …