Effects of systemic inflammation on cerebral function are not clear, as both inflammation-induced encephalopathy as well as stress-hormone mediated alertness have been described. Experimental endotoxemia (2 ng/kg Escherichia coli lipopolysaccharide [LPS]) was induced in 15 subjects, whereas 10 served …

Many people experience with advancing age complaints caused by degenerative changes of the cartilage in their joints, often leading to osteoarthritis (OA). Prevention and/or reduction of OA may include stimulation of the formation of new cartilage, the reduction of degenerative changes and the treatment …