Systemic sclerosis (SSc) is an autoimmune disease which is characterized by vasculopathy, tissue fibrosis and activation of the innate and adaptive immune system. Clinical features of the disease consists of skin thickening and internal organ involvement. Due to the heterogeneous nature of the disease …

Modern safety thinking and models focus more on systemic factors rather than simple cause-effect attributions of unfavourable events on the behaviour of individual system actors. This study concludes previous research during which we had traced practices of new safety thinking practices (NSTPs) in aviation …

In this paper we present a review of existing aviation safety metrics and we lay the foundation for our four-years research project entitled “Measuring Safety in Aviation – Developing Metrics for Safety Management Systems”. We reviewed state-of-the-art literature, relevant standards and regulations, …

In the debate about smart cities, an alternative to a dominant top-down, tech-driven solutionist approach has arisen in examples of ‘civic hacking’. Hacking here refers to the playful, exploratory, collaborative and sometimes transgressive modes of operation found in various hacker cultures, this time …

This paper presents an analytical and intervention model that introduces new vocabulary to explore, describe and build collective futures through shared understanding of complexities facing local and regional developments. This new vocabulary builds on evolutionary and complexity approaches applied to …

Now, that the European cities are overcoming the recent economic challenges, they accelerate the development of major housingschemes to accommodate their growing urban population. Amsterdam for instance, sets out to construct 50,000 new homes by 2025. Parallel to this, the City Council presented a new …

The adaptation of urbanised areas to climate change is currently one of the key challenges in the domain of urban policy. The diversity of environmental determinants requires the formulation of individual plans dedicated to the most significant local issues. This article serves as a methodic proposition …

Change agent capacity-building compendium.Due to increasing globalization, technological advances and sociological changes, the world is becoming more complex than ever. Complexity has gone from large systems, to organizational and individual levels. Today it concerns all aspects of society. The will …

The research explored how a Dutch energy cluster embedded within a larger context of European and global developments reflected complex dynamics due to changes in its context. The case study explored Energy Valley of the Netherlands, a peripheral region that meets the challenge of energy transition, …