The European Higher Education Area (EHEA) requires changes in the way universities are managed. It is an opportunity for correcting imbalances whilst at the same time being a challenge that can mark important differences between universities. This study seeks to identify the challenges and information/training …

An efficient four-step biotransformation-mediated synthesis of (1S)-1-(2,6-dichloro-3-fluorophenyl)ethanol in enantiomerically pure form is described. This compound is a key intermediate required for the preparation of PF-2341066, a potent inhibitor of c-Met/ALK that is currently in clinical development. …